April 22 coronavirus news

By Nicholas Pearce, Ivana Kottasová and Sophie Jeong, CNN

Updated 3:03 AM ET, Mon April 26, 2021
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1:46 a.m. ET, April 22, 2021

The CDC is putting together further guidance for vaccinated Americans, White House says

From CNN's DJ Judd 

A sheet of "I Got My Covid-19 Vaccine" stickers are seen at the St. Joseph's Community Campus in downtown Reading, Pennsylvania on April 21.
A sheet of "I Got My Covid-19 Vaccine" stickers are seen at the St. Joseph's Community Campus in downtown Reading, Pennsylvania on April 21. Ben Hasty/MediaNews Group/Reading Eagle/Getty Images

The US Centers for Disease Control and Prevention are “in the process of putting together further guidance” for vaccinated Americans, White House senior adviser for Covid-19 response Andy Slavitt told CNN.

The CDC is “not always going to be as fast as everybody wants them to be, because they like to study the data and make sure that they're, generally speaking, not putting things out that they will have to take back,” Slavitt said. 
“But I'm quite confident that over the next couple of weeks and months, those questions will be answered, those guidelines will absolutely loosen. And they're going to be science-based but also hopefully very practical.”

Slavitt also touted the White House’s newly announced efforts to counter plateauing vaccination rates by offering incentives for businesses to allow their employees to get vaccinated.

“One of the things that's changing most rapidly is we have vaccinated the lion's share of people over 65, and we're doing pretty well with people over 50 -- this week we have started to move in earnest to vaccinate working Americans," he said.

1:48 a.m. ET, April 22, 2021

Only 2 "breakthrough" infections among hundreds of fully vaccinated people, new study finds

From CNN's Jacqueline Howard

For fully vaccinated people, the risk of still getting Covid-19 -- described as "breakthrough infections" -- remains extremely low, a new study out of New York suggests.

Among 417 employees at Rockefeller University who were fully vaccinated with either the Pfizer or Moderna shots, two of them or about .5%, had breakthrough infections later, according to the study published on Wednesday in the New England Journal of Medicine.

"We have characterized bona fide examples of vaccine breakthrough manifesting as clinical symptoms," the researchers wrote in their study. "These observations in no way undermine the importance of the urgent efforts being taken at the federal and state levels to vaccinate the U.S. population. They also lend support to efforts to advance a new vaccine booster (as well as a pan-coronavirus vaccine) to provide increased protection against variants."

The researchers, from Rockefeller University, found that coronavirus variants with several differences from the original virus caused the breakthrough infections.

A variant that infected one of the patients had the mutation E484K, which was first found in the B.1.351 variant originally identified in South Africa. E484K has been called an "escape mutant" because it has shown it might be able to escape some of the antibodies produced by coronavirus vaccines. One of the mutations found in both study participants' infections included D614G, which emerged early in the pandemic.

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