June 30 coronavirus news

By Nectar Gan, Adam Renton, Melissa Macaya, Meg Wagner and Mike Hayes, CNN

Updated 12:02 a.m. ET, July 1, 2020
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7:30 p.m. ET, June 30, 2020

Coronavirus vaccines need to have 50% efficacy or better, FDA says in new guidance

From CNN’s Maggie Fox

Any new coronavirus vaccine will have to work at least 50% better than a placebo in preventing infection or serious disease in people, the US Food and Drug Administration said in new guidance released Tuesday to vaccine makers.

New vaccines should also be at least as safe as other vaccines against infectious diseases, and testing should include three to four weeks’ follow-up in volunteers to make sure there are no adverse events, the FDA said. 

“To ensure that a widely deployed Covid-19 vaccine is effective, the primary efficacy endpoint point estimate for a placebo-controlled efficacy trial should be at least 50%,” the agency said in its guidance.

While that’s not considered desirable for a vaccine, it’s within the range of current influenza vaccines, for instance. In some years flu vaccines can have 40% efficacy or even less in preventing infection. That compares to measles vaccines, which have about 97% efficacy after two doses, according to the US Centers for Disease Control and Prevention.

The FDA also says that vaccine makers should specifically ask about adverse events in volunteers for at least seven days after they get the vaccine, and then wait for any unsolicited reports of side-effects for 21 to 28 days after each vaccination. And any study should include watching for serious events requiring a medical intervention for at least six months after the last vaccination.

“All pregnancies in study participants for which the date of conception is prior to vaccination or within 30 days after vaccination should be followed for pregnancy outcomes, including pregnancy loss, stillbirth, and congenital anomalies,” the FDA adds in its guidance.

But it doesn’t say pregnant women should be excluded.

And companies making vaccines using new and untested designs will have to test in animals first, the FDA said.

The guidelines also consider reports that show Blacks and Hispanics are especially hard hit by the virus.

“FDA strongly encourages the enrollment of populations most affected by COVID-19, specifically racial and ethnic minorities,” the guidelines say.

7:40 p.m. ET, June 30, 2020

Miami-Dade mayor says he will sign order closing restaurants nightly at midnight 

From CNN's Jamiel Lynch

Miami-Dade Mayor Carlos Gimenez said he will be signing an order today closing restaurants in the county nightly at midnight.

"We've seen some restaurants taking advantage of that order and basically turning themselves into nightclubs after 12 o'clock," Gimenez told CNN’s Jim Acosta.

"They are converting themselves into nightclubs after 12 o'clock and we have seen a sharp rise in the number of young people," he added.

Gimenez said that not complying with the order is a misdemeanor and violators can be fined and spend up to 180 days in jail.

Official conducted 7,000 inspections on businesses today to "make sure they were complying," he said.

"The vast majority are complying but again we think it's more of a problem with young people, they're not complying," Gimenez said.

7:00 p.m. ET, June 30, 2020

More than 40% of coronavirus cases in small Italian village were asymptomatic, study finds

From CNN's Shelby Lin Erdman

More than 40% of people infected with coronavirus in a small village in northern Italy had no symptoms during a coronavirus outbreak earlier this year, an international team of researchers reported Tuesday.

Yet the people without symptoms had virtually the same viral load – that’s the amount of virus in their systems – as people who did have symptoms, the researchers wrote in a pre-print, non-peer reviewed report published in the journal Nature.

The team tested most of the residents of Vo after an outbreak forced a two-week lockdown of the village in February.

They found 42.5% of people with confirmed Covid-19 infections were asymptomatic, meaning they “did not have symptoms at the time of the swab testing and did not develop symptoms afterward,” researchers Enrico Lavezzo and Elisa Franchin of the University of Padova in Italy and colleagues across Europe wrote. “On the first survey, which was conducted around the time the town lockdown started, we found a prevalence of infection of 2.6%, they wrote. “On the second survey, which was conducted at the end of the lockdown, we found a prevalence of 1.2%.”

This is the first definitive assessment of the rate of asymptomatic infection in Covid-19 cases since the pandemic began, Lavezzo and Franchin’s team said.

“This figure is of enormous value as it informs estimates and decisions regarding the further dealing with the epidemic in many countries,” they wrote. 

“This study sheds new light on the frequency of asymptomatic SARS-CoV-2 infection, their infectivity (as measured by the viral load) and provides new insights into its transmission dynamics and the efficacy of the implemented control measures,” they added.

 

6:47 p.m. ET, June 30, 2020

Brazil nearly doubles number of Covid-19 daily death count from previous day

From CNN's Rodrigo Pedroso, Shasta Darlington and Claudia Rebaza

Workers monitor data inside the Ministry of Science, Innovation, Technology and Communication's crisis management command center in Sao Paulo, Brazil, on Tuesday, June 30. Brazil's telecommunications operators have provided the government with geolocation data to help monitor population mobility, concentration and risk of contamination in an effort to help stop the spread of the coronavirus.
Workers monitor data inside the Ministry of Science, Innovation, Technology and Communication's crisis management command center in Sao Paulo, Brazil, on Tuesday, June 30. Brazil's telecommunications operators have provided the government with geolocation data to help monitor population mobility, concentration and risk of contamination in an effort to help stop the spread of the coronavirus. Jonne Roriz/Bloomberg/Getty Images

Brazil's health ministry reported 1,280 new Covid-19 deaths in the past 24 hours, nearly doubling the previous day's count.  

The country's death toll stands at 59,594 as Rio de Janeiro state alone surpassed 10,000 total deaths from the virus Tuesday, according to Rio's state health secretary.

The national health ministry also recorded another 33,846 new cases Tuesday, bringing the country's total to at least 1,402,041.

This comes after a new survey published Tuesday showed that fewer Brazilians are sheltering at home, although showing they are increasingly afraid of contracting the virus. 

At the end of June, 47% of Brazilians were "very afraid" of contracting the novel coronavirus, up from 36% in mid-March when several states ordered all but essential businesses to close, according to the Datafolha polling firm.

Nonetheless, fewer Brazilians reported staying at home. Those who reported remaining totally isolated fell to 12% from 18% and those who said they were taking precautions but still leaving home to work and perform other activities was up to 34% from 24%.

6:40 p.m. ET, June 30, 2020

Here's the latest coronavirus update from Vermont

From CNN's Rob Frehse

Vermont will allow people from low-risk counties in other states to visit effective July 1, according to the Vermont Health Department.

The additional states include: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, Virginia and West Virginia, as well as the District of Columbia, the health department announced in a statement.

New York, Maine, Vermont, New Hampshire, Rhode Island and Massachusetts were previously included.

Vermont defines low risk as any county with less than 400 active cases of Covid-19 per one million residents, basing their data off Johns Hopkins University.

If not exempt by the low risk guidelines above, Vermont allows individuals outside of New England and New York to quarantine in their home state for 14 days, or seven days followed by a negative test.

Vermont also “strongly encourages” out-of-state travelers to register with Sara Alert when they arrive in state to get two weeks of reminders to check for Covid-19 symptoms.

“All our efforts and day-to day actions have been critical to slowing the virus’ spread,” the state's health department said in a release Tuesday. “But our progress is fragile, and we all have an ongoing responsibility in keeping it from roaring back. Stay home when you’re sick. Wash your hands — a lot. Keep a physical distance of at least 6 feet. Wear a face mask when around others.”
7:13 p.m. ET, June 30, 2020

Texas reports highest daily total of Covid-19 cases

From CNN's Raja Razek

A demonstrator holds up a sign during a "Bar Lives Matter" protest in Austin, Texas, on June 30. Gov. Greg Abbott's ordered to close bars on June 26.
A demonstrator holds up a sign during a "Bar Lives Matter" protest in Austin, Texas, on June 30. Gov. Greg Abbott's ordered to close bars on June 26. Sergio Flores/Bloomberg via Getty Images

Texas reported 6,975 new Covid-19 cases on Tuesday.

This is the state's highest daily number of cases, bringing the total to at least 159,986 cases. At least 2,424 people have died from the virus in the state.

The reporting comes after Texas Gov. Greg Abbott ordered for bars to close following the rise in cases. He also paused more reopenings for the state.

WATCH:

6:14 p.m. ET, June 30, 2020

Toronto to require face masks in indoor public places

From CNN’s Rebekah Riess

People seen wearing face masks  in Toronto, Ontario, Canada on May 31.
People seen wearing face masks in Toronto, Ontario, Canada on May 31. Creative Touch Imaging Ltd./NurPhoto via Getty Images/FILE

Toronto City Council voted unanimously in favor of requiring face masks in all indoor public places starting July 7 to help stop the spread of Covid-19, according to a statement from the city. 

Businesses must adopt a policy to ensure masks or face coverings are worn in indoor public spaces under their control.

It will apply to all indoor spaces that are openly accessible to the public, including retail stores, grocery stores, restaurants, bars, gyms, swimming pools, churches, and common areas in hotels, motels and short-term rentals, among others.

The mandate will expire the day of Toronto’s first council meeting after their summer recess, currently scheduled for September 30, unless extended by council.

Toronto’s medical officer of health will review the recommendations regarding masks and face coverings on a monthly basis and report if any changes are needed before that date, according to the statement.

6:08 p.m. ET, June 30, 2020

Colorado governor orders bars and nightclubs to close

From CNN's Jessica King

Bars and nightclubs that do not serve food must close during the month of July, Colorado Gov. Jared Polis announced at a briefing Tuesday.

Keeping them open is “too big a risk,” he said. They will be closed for in-person service only, and will be allowed to sell alcohol as a take-out option.

The move comes amid an uptick of Covid-19 cases in many states across the nation, including Colorado.  

It’s possible that areas of Colorado that have improvement will be able to reopen bars at nightclubs at some point during July, he said.  

Bars that now serve food and function as restaurants can stay open provided there is social distancing and people remain six feet apart. Customers must also be seated with their own party. 

5:58 p.m. ET, June 30, 2020

Traveler from the US infects 71 people in China with Covid-19, research finds

From CNN’s Naomi Thomas

A woman returning home to China from the US carried coronavirus back with her and sparked an outbreak that ended up infecting at least 71 people, researchers reported Tuesday.

It started with an elevator ride, the researchers report in the Centers for Disease Control and Prevention’s journal Emerging Infectious Diseases. 

The woman returned to Heilongjiang Province from a trip to the US on March 19, about a week after the last coronavirus case was diagnosed in the province. She had no symptoms and tested negative for coronavirus, but was asked to quarantine at home. 

No one suspected anything was wrong until a man with no obvious connection to the traveler suffered a stroke. It turns out he had been at a party with relatives of a neighbor living in the same building as the traveler.

When the researchers in China finally put the story together, they determined that the traveler must have somehow contaminated the elevator in her building. Her downstairs neighbor, who used the same elevator, also got infected, and she in turn infected her mother and her mother’s boyfriend. They went to a party and infected the stroke patient and his sons. 

The stroke patient and two of his sons went to two hospitals. At least 28 people were infected at the first hospital and 20 more were infected when he was moved to a second facility.

When the Chinese Center for Disease Control and Prevention investigated the genetic makeup of the virus found in this new outbreak, they found it was different from strains previously seen in China. The viruses in the patients were genetically identical or at least very similar, which led them to believe the virus originated overseas. 

When investigators learned that a neighbor of one of the cases had recently returned from abroad, they tested her again. She was not currently infected but had antibodies to the virus, indicating a previous infection. They designated her A0, meaning she was the first case. “Therefore, we believe A0 was an asymptomatic carrier and that B1.1 (her neighbor) was infected by contact with surfaces in the elevator in the building where they both lived,” they wrote. Other residents in the building all tested negative.

“As of April 22, 2020, A0 remained asymptomatic, and a total of 71 SARS-CoV-2–positive cases had been identified in the cluster,” the researchers wrote.

“Our results illustrate how a single asymptomatic SARS-CoV-2 infection could result in widespread community transmission.”