June 5 coronavirus news

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2:02 a.m. ET, June 5, 2020

More than 1,000 coronavirus deaths reported in the US in 24 hours

There are now 1,872,660 cases of the novel coronavirus in the US, according to Johns Hopkins University, after 21,140 new infections were reported on Thursday.

So far, 108,211 people have died from the disease, with 1,036 new fatalities reported in the previous 24 hours.

The totals includes cases from all 50 states, the District of Columbia and other U.S. territories, as well as repatriated cases. 

For the latest updates, you can follow CNN's map which refreshes every 15 minutes:

4:39 a.m. ET, June 5, 2020

US biotech firm contracted to deliver 10 million doses of coronavirus vaccine candidate

From CNN Health’s Jen Christensen

Dr. Rhonda Flores looks at protein samples at Novavax labs, which is developing a vaccine for the coronavirus, in Rockville, Maryland, on March 20.
Dr. Rhonda Flores looks at protein samples at Novavax labs, which is developing a vaccine for the coronavirus, in Rockville, Maryland, on March 20. Andrew Caballero-Reynolds/AFP/Getty Images

Novavax, Inc., a Maryland-based biotech company, said Thursday it landed a major US Department of Defense contract to make its coronavirus vaccine candidate. 

The Defense Department will provide up to $60 million in funding for the vaccine, which goes by the experimental name NVX-COV2373. The company will make several of the components in the US.  

Novavax will deliver 10 million doses to the Department of Defense in 2020 that could be used in late-stage clinical trials or under an Emergency Use Authorization if the US Food and Drug Administration approves the vaccine.

How far away is the vaccine?: Novavax started a Phase I safety trial with volunteers in May. Those results are expected by July. If successful, Novavax will test in a larger number of patients. 

Novavax is ahead of several competitors, including Johnson & Johnson, Sanofi and Merck, that are developing a vaccine but are yet started clinical trials, according to the World Health Organization.

Pharmaceutical companies Moderna and AstraZeneca have candidates in clinical trials.  

1:37 a.m. ET, June 5, 2020

Mexico announces a record increase in new coronavirus cases for the third straight day

From CNN's Matt Rivers in Mexico City

Workers bury an alleged victim of Covid-19 at the Municipal Pantheon of Valle de Chalco, Mexico, on June 4.
Workers bury an alleged victim of Covid-19 at the Municipal Pantheon of Valle de Chalco, Mexico, on June 4. Alfredo Estrella/AFP/Getty Images

Mexico health officials said Thursday they had confirmed a record 4,442 new cases -- bringing the overall number of infections in the country to 105,680. 

It marked the largest daily increase in new coronavirus cases for the third straight day

Mexico also recorded 816 additional deaths, taking the total toll to 12,545.

12:39 a.m. ET, June 5, 2020

It's 1.30 a.m. in Brasilia and 12.30 p.m. in Hong Kong. Here are today's top coronavirus headlines

  • Global infections top 6.6 million: A total of 6,635,004 cases of Covid-19 have been reported worldwide, including at least 391,000 deaths, according to Johns Hopkins University.
  • Brazil death toll surpasses Italy: The South American country now has the third-highest number of coronavirus fatalities in the world, behind the US and the United Kingdom. Brazil's health ministry reported 34,021 deaths as of Thursday.
  • Mexico records largest rise yet: Mexico has more than 105,600 total cases after 4,442 new infections were reported Thursday -- its largest single-day increase to date.
  • Study into Trump drug withdrawn: Research disputing the effectiveness of hydroxychloroquine as a treatment for coronavirus has been retracted after questions were raised over the data. Hydroxychloroquine was recommended as a "game-changer" by US President Donald Trump.
  • US forecast worsens: A forecast published by the US Centers for Disease Control and Prevention now projects more than 127,000 coronavirus-related deaths in the country by June 27.
  • Face masks mandatory in UK: Everyone on public transport in the UK will have to wear face coverings from June 15, the government announced Thursday.

12:09 a.m. ET, June 5, 2020

Brazil passes Italy's coronavirus death toll with another daily record

From journalist Rodrigo Pedroso in Sao Paulo, CNN’s Shasta Darlington in Sao Paulo, and CNN’s Taylor Barnes in Atlanta

Newly dug, empty graves fill the Sao Luiz cemetery where Covid-19 victims will be buried in Sao Paulo, Brazil, on Thursday, June 4.
Newly dug, empty graves fill the Sao Luiz cemetery where Covid-19 victims will be buried in Sao Paulo, Brazil, on Thursday, June 4. Andre Penner/AP

Brazil registered a record 1,473 more coronavirus-related fatalities in the 24 hours to Thursday, its health ministry reported, with the country’s death toll now at 34,021.  

The new fatalities push Brazil's toll past that of Italy, which has reported 33,689 deaths so far, according to Johns Hopkins University's tally

Brazil now has the third-highest death toll worldwide, behind the United States and the United Kingdom.

The health ministry also said it registered 30,925 new coronavirus cases over the previous 24 hours, increasing the nationwide total to 614,941.

Senior health ministry official Eduardo Macário acknowledged that the country is facing difficulties even measuring the extent of coronavirus contagion. 

“The government has been working to reduce under-reporting, expanding the testing capacity,” he said at a press conference. 
11:39 p.m. ET, June 4, 2020

A common heartburn drug may have helped 10 patients at home with coronavirus

From CNN Health’s Elizabeth Cohen

Famotidine, a generic for Pepcid, is seen on a table in Alameda, California, on April 29.
Famotidine, a generic for Pepcid, is seen on a table in Alameda, California, on April 29. Shutterstock

It's a common, over-the-counter drug used for treating heartburn -- yet famotidine may have given relief to patients with the novel coronavirus.

Ten patients home sick with Covid-19 took famotidine, the active ingredient in Pepcid, and in all 10 cases, their symptoms improved, according to a study published Thursday. None were hospitalized, and all survived.  

“All patients noticed a rapid improvement in their condition within 24 to 48 hours of starting famotidine,” according to the report, published Thursday in the medical journal Gut. “These findings suggest that famotidine may affect the course of COVID-19.” 

Read more here:

11:13 p.m. ET, June 4, 2020

Pharma giant promises 300 million doses of Covid-19 vaccine candidate by year's end

From CNN Health’s Jen Christensen

The AstraZeneca building in Luton, Britain, on May 18.
The AstraZeneca building in Luton, Britain, on May 18. Tim Ireland/Xinhua/Getty Images

AstraZeneca announced Thursday that it will make 300 million doses of a Covid-19 vaccine candidate from Oxford University scientists by the end of 2020.

The UK pharma giant signed what it is calling a “landmark” $750 million deal with the Vaccine Alliance Gavi and the Coalition for Epidemic Preparedness Innovations (CEPI).

CEPI will manufacture the vaccine while Gavi will lead the procurement efforts. 

The company also made a licensing deal with India’s Serum Institute to make 1 billion doses of the vaccine available in India, as well as developing countries.

The Bill and Melinda Gates Foundation, along with the World Health Organization’s Access to Covid-19 Tools Accelerator, will make sure that the vaccine is fairly distributed across the world.

Wait ... a vaccine already?: Typically, companies wait to start the manufacturing process until after it is known the vaccine is safe and works. But with the threat of the pandemic, several drug companies have accelerated this process.

The Oxford vaccine is currently being tested in about 10,000 adult volunteers.

The company said on its website that it realizes the vaccine may not work, but at no profit, it is “committed to progressing the clinical programme with speed and scaling up manufacturing at risk” and will make sure that it is available to people around the world “including to those in countries with the lowest means.”

10:49 p.m. ET, June 4, 2020

Patients with high blood pressure are twice as likely to die from coronavirus: study

From CNN Health’s Maggie Fox

Coronavirus patients with high blood pressure are twice as likely to die from the infection, a new international study found. 

High blood pressure has been known to worsen the risk of serious symptoms, but the study -- published in the European Heart Journal -- shows just how bad the risk is.

The international team of researchers, led by Fei Li and Ling Tao of the department of cardiology at Xijing Hospital in Xi'an, China, studied the records of 2,866 patients treated in Wuhan, where the coronavirus outbreak emerged.

Just under 30% of them had high blood pressure.

"Soon after we started to treat COVID-19 patients in early February in Wuhan, we noticed that nearly half of the patients who died had high blood pressure, which was a much higher percentage compared to those with only mild COVID-19 symptoms,” Tao said in a statement.

The team found that 4% of patients with high blood pressure died, compared to 1.1% of those without high blood pressure.

After some adjustments for differences among the patients, that worked out to a doubled risk of dying for the patients with high blood pressure. And 7.9% of patients who had stopped taking their blood pressure medications died.

10:48 p.m. ET, June 4, 2020

More than 5,000 people have died from coronavirus in Peru

From CNN’s Taylor Barnes in Atlanta

Relatives carry the coffin of a suspected Covid-19 victim at the Nueva Esperanza cemetery on the outskirts of Lima, Peru, on May 28.
Relatives carry the coffin of a suspected Covid-19 victim at the Nueva Esperanza cemetery on the outskirts of Lima, Peru, on May 28. Rodrigo Abd/AP

Peru reported 137 new coronavirus-related deaths Thursday – raising the national death toll to 5,031, according to the country’s health ministry. 

The total number of cases rose to 183,198, an increase of 4,284 from the previous day. 

Peru has the second-highest number of coronavirus cases in Latin America, after Brazil, according to Johns Hopkins University's tally.