At least 1,950 flights within, into, or out of the US have been canceled, FlightAware reports.
New York City's John F. Kennedy International Airport said it canceled at least 450 of it's flights today:
6:54 a.m. ET, March 7, 2018
How this storm will affect the East Coast's biggest cities
From CNN's Madison Park and Amir Vera
New York City could get between 4 and 8 inches of snow. New York City public schools will be open, officials said. The heaviest precipitation will occur Wednesday morning into the evening, according to the National Weather Service New York office.
Philadelphia could also get about 4 to 6 inches of snow, according to the NWS' snowfall estimates, which advised against unnecessary travel after 7 a.m. City schools will be closed Wednesday, and all after-school activities canceled.
Boston will likely see a slushy 1 to 3 inches of snow, which may be more rain than snow. But areas 20 miles inland of Boston are expected to get about 10 or more inches of snow.
6:49 a.m. ET, March 7, 2018
More than 40,000 customers are still without power after previous winter storm
From CNN's Evan Simko-Bednarski
There are at least 41,750 customers still without power from Virginia to New England, according to area power companies, as of 6:30 a.m. ET Wednesday,
This comes as a second nor'easter in a span of a week is expected to drop heavy snow and hurl strong winds across parts of the storm-weary East Coast.