American teens are experiencing a rise in mental health challenges according to a new study from the Centers for Disease Control and Prevention. This includes high levels of sadness amid significant declines in overall well-being, especially among girls and LGBQ+ youth. Could social media be part of the problem? Dr. Sanjay Gupta turns to Professor Keneisha Sinclair-McBride, a child psychologist at Boston Children’s Hospital, to unpack this data and discuss the connection between social media and youth mental health. Sanjay also asks his teenage daughter, Sky, about how social media affects our self-esteem.