After a half-century of waiting, Wally Funk — who trained for NASA’s Mercury program but was denied the opportunity to go to space — is finally getting her time amongst the stars. She’s been selected by the world’s richest man, Jeff Bezos, to accompany him, his brother, and an as-yet unknown auction winner on a suborbital trip on July 20th. The SpaceX Crew Dragon spacecraft’s systems were warning the crew of a “significant” issue, Isaacman said. They’d spent months poring over SpaceX manuals and training to respond to in-space emergencies, so they leaped into action, working with SpaceX ground controllers to pinpoint the cause of the error. As it turned out, the Crew Dragon wasn’t in jeopardy. But the on board toilet was. Nothing in space is easy, including going to the bathroom. In a healthy human on Earth, making sure everything ends up in the toilet is usually a matter of simple aim. But in space, there is no feeling of gravity. There’s no guarantee that what comes out will go where it’s supposed to. Waste can — and does — go in every possible direction. To solve that problem, space toilets have fans inside them, which are used to create suction. Essentially they pull waste out of the human body and keep it stored away. And the Crew Dragon’s “waste management system” fans were experiencing mechanical problems. That is what tripped the alarm the crew heard. Scott “Kidd” Poteet, an Inspiration4 mission director who helped oversee the mission from the ground, tipped reporters off about the issue in an interview with CBS. Poteet and SpaceX’s director of crew mission management later confirmed there were “issues” with the waste management system at a press conference but didn’t go into detail, setting off an immediate wave of speculation that the error could’ve created a disastrous mess. When asked directly about that on Thursday, however, Isaacman said “I want to be 100% clear: There were no issues in the cabin at all as it relates to that.” But Isaacman and his fellow travelers on the Inspiration4 mission did have to work with SpaceX to respond to the problem during their three-day stay in orbit, during which they experienced numerous communications blackouts, highlighting the importance of the crew’s thorough training regimen. “I would say probably somewhere around 10% of our time on orbit we had no [communication with the ground], and we were a very calm, cool crew during that,” he said, adding that “mental toughness and a good frame of mind and a good attitude” were crucial to the mission. “The psychological aspect is one area where you can’t compromise because…there were obviously circumstances that happened up there where if you had somebody that didn’t have that mental toughness and started to react poorly, that really could’ve brought down the whole mission,” Isaacman said. SpaceX did not respond to CNN Business’ requests for comment. The toilet anecdote also highlights a fundamental truth about humanity and its extraterrestrial ambitions — no matter how polished and glitzy we may imagine our space-faring future, biological realities remain. Excreta in space, a history Isaacman was — as numerous astronauts before him — bashful when it came to discussing the “toilet situation.” “Nobody really wants to get into the gory details,” Isaacman said. But when the Inspiration4 crew talked to some NASA astronauts, they said “using the bathroom in space is hard, and you’ve got to be very — what was the word? — very kind to one another.” He added that, despite the on-board toilet issues, nobody suffered any accidents or indignities. “I don’t know who was training them, but we were able to work through it and get [the toilet] going even with what was initially challenging circumstances, so there was nothing ever like, you know, in the cabin or anything like that,” he said. Figuring out how to safely relieve oneself in space was, however, was a fundamental question posed at the dawn of human spaceflight half a century ago, and the path to answers was not error-free. During the 1969 Apollo 10 mission — the one that saw Thomas Stafford, John Young and Eugene Cernan circumnavigate the moon — Stafford reported back to mission control on Day Six of the mission that a piece of waste was floating through the cabin, according to once-confidential government documents. “Give me a napkin, quick,” Stafford is recorded as saying a few minutes before Cernan spots another one: “Here’s another goddamn turd.” The feces collection process at the time, a NASA report later revealed, was an “extremely basic” plastic bag that was “taped to the buttocks.” “The fecal bag system was marginally functional and was described as very ‘distasteful’ by the crew,” an official NASA report from 2007 later revealed. “The bags provided no odor control in the small capsule and the odor was prominent.” In-space toilets have evolved since then, thanks to strenuous efforts from NASA scientists, as journalist Mary Roach, author of “Packing for Mars,” told NPR in 2010. “The problem here is you’ve got this very elaborate space toilet, and you need to test it. Well, you’ve got to, you know, haul it over to Ellington Field, board it onto a zero-gravity simulator — a plane that does these elaborate up-and-down arcs — and then you’ve got to find some poor volunteer from the Waste System Management Office to test it. And I don’t know about you, but, I mean, to do it on demand in 20 seconds, now that is asking a lot of your colon. So it’s very elaborate and tricky.” And, Roach writes in “Packing for Mars,” astronaut potty training is no laughing matter. “The simple act of urination can, without gravity, become a medical emergency requiring catheterization and embarrassing radio consults with flight surgeons,” she wrote. And because urine behaves differently inside the bladder in space, it can be very difficult to tell when one needs to go. Adapting to space The human body is evolutionarily designed for life on Earth, with its gravity, oxygen-rich air and predictable ecological cycles. It is specifically not designed to float disoriented in weightlessness, a fact that has caused numerous astronauts to experience a sickening queasiness, especially during the first couple of days in orbit. “I vomited 93 minutes into my first flight,” NASA astronaut Steven Smith, a veteran of four Space Shuttle missions, told one journalist. “That was the first of 100 times over the four flights. It’s odd going to a job where you know you’re going to throw up.” NASA has a formal term for the illness — Space Adaptation Syndrome, which in one paper it estimates about 80% of astronauts have experienced. Isaacman said that during the Inspiration4 mission, he didn’t feel the urge to vomit. But adjusting to microgravity can be uncomfortable. “It’s just this pooling in your head, like when you hang upside down on your bed,” he told CNN Business. “But you have to kind of find a way to just ignore it and work through it…About a day later, it kind of balances out and you don’t notice it as much.” Not all of his crewmates were as lucky. Hayley Arceneaux, a 29-year-old cancer survivor who served as Inspiration4’s medical officer, had to administer Phenergan shots — an antihistamine used to treat motion sickness to combat nausea, Isaacman said. The inescapable fact is that humans will be battling maladies for as long as we continue to look at space and see it as place we should be going. That’s why many journalists, including Roach, have questioned our tendency to romanticize space travel and downplay the harsh realities and risks. But despite the discomfort, Isaacman said he has zero regrets about his decision to spend roughly $200 million on a three-day spaceflight. “I hope that this is a model for future missions,” he said, adding that he believes in SpaceX’s mission to eventually support entire colonies of people living in outer space. The US military is racking up deals with commercial rocket companies to explore the idea of using rockets typically tasked with launching satellites or astronauts to shuttle military cargo around the world at record speeds.