SAN RAFAEL, CA - JANUARY 28:  Rhiannon Griffith-Bowman smokes an E-Cigarette at Digital Ciggz on January 28, 2015 in San Rafael, California. The California Department of Public Health released a report today that calls E-Cigarettes a health threat and suggests that they should be regulated like regular cigarettes and tobacco products.  (Photo by Justin Sullivan/Getty Images)
What are people vaping?
02:07 - Source: CNN
CNN  — 

Missouri health officials announced on Thursday the vaping-related death of a man in his mid-40s. This is the United States’ eighth death linked to severe lung injury and illness tied to e-cigarettes.

The Missouri Department of Health and Senior Services said the man had normal lung function before he started to vape in May. He developed mild respiratory symptoms that worsened, and was hospitalized on August 22.

“This is an unfortunate case of a young man with no prior lung illness who started vaping because of chronic pain issues,” Dr. Michael Plisco, Mercy Hospital St. Louis critical care pulmonologist and medical director of Mercy’s extracorporeal membrane oxygenation (ECMO) program said in a media release. “He started out with shortness of breath and it rapidly progressed and deteriorated, developing into what is called acute respiratory distress syndrome (ARDS). Once the lungs are injured by vaping, we don’t know how quickly it worsens and if it depends on other risk factors.”

Vaping-related illnesses have been linked to seven previous deaths – two in California and one each in Kansas, Illinois, Indiana, Minnesota, Oregon. CDC health officials said on Thursday they expect more deaths to be reported.

There have been 530 confirmed and probable cases of lung injuries related to e-cigarettes as of September 17, the US Centers for Disease Control and Prevention said Thursday. That’s 150 more than was reported on September 11.

As of September 17, there have been vaping-related illnesses in 38 states and one US territory, the CDC said. Among the cases for which patients’ sex and age are available, 72% are in men, 67% are in people ages 18 to 34, 16% are in people younger than 18 and 17% are in people age 35 and older. More than half of the cases are in people younger than 25.

Still, health officials said they haven’t found a definitive cause or a clear connection between cases, and they warned that patients worried about becoming ill from vaping should refrain from using e-cigarettes.

Hundreds of cases, multiple substances

On Thursday, officials from CDC, FDA and states complex investigations, involving hundreds of patients – including some who are reluctant or too ill to talk with investigators – and multiple substances.

“I wish we had more answers,” Dr. Anne Schuchat, principal deputy director of the CDC, said during a media briefing on Thursday.