Barcelona
Barcelona's coach Luis Enrique and his daughter Xana wave a flag after the UEFA Champions League Final football match between Juventus and FC Barcelona at the Olympic Stadium in Berlin on June 6, 2015. FC Barcelona won the match 1-3. AFP PHOTO / LLUIS GENE (Photo credit should read LLUIS GENE/AFP/Getty Images)
PHOTO: LLUIS GENE/AFP/AFP/Getty Images
Now playing
00:52
Football manager Luis Enrique announces daughter's death
PHOTO: Getty Images
Now playing
02:17
Alexey Navalny arrested on his return to Moscow
PHOTO: CNN
Now playing
01:47
John King: It's a horrific time to become president
A sign for the National Security Agency (NSA), US Cyber Command and Central Security Service, is seen near the visitor
A sign for the National Security Agency (NSA), US Cyber Command and Central Security Service, is seen near the visitor's entrance to the headquarters of the National Security Agency (NSA) after a shooting incident at the entrance in Fort Meade, Maryland, February 14, 2018. - Shots were fired early Wednesday at the ultra-secret National Security Agency, the US electronic spying agency outside Washington, leaving one person injured, officials said. Aerial footage of the scene from NBC News showed a black SUV with numerous bullet holes in its windshield crashed into concrete barriers at the main entrance to the NSA's headquarters in Fort Meade, Maryland. (Photo by SAUL LOEB / AFP) (Photo by SAUL LOEB/AFP via Getty Images)
PHOTO: Saul Loeb/AFP/Getty Images
Now playing
01:31
Christopher Miller orders NSA chief to install Trump loyalist as agency's top lawyer
PHOTO: CNN Weather
Now playing
02:41
US to rejoin the Paris Climate Accord on Bidens First Day
Now playing
02:38
Biden: Science team 'among the brightest, most dedicated'
Mike Pence remarks vpx
Mike Pence remarks vpx
PHOTO: Senate TV
Now playing
02:27
New timeline shows just how close rioters got to Pence and his family
MyPillow notes
MyPillow notes
PHOTO: Jabin Botsford
Now playing
02:21
Photographer snaps notes of MyPillow CEO after visiting Trump
PHOTO: CNN
Now playing
02:31
Teachers feel pressure as schools weigh in-person classes
PHOTO: CNN
Now playing
01:48
FBI warns of potential armed protests across country
Staffer White House move out
Staffer White House move out
PHOTO: CNN
Now playing
01:36
Moving trucks spotted at White House as staffers clean out their desks
southern california january strong winds low humidity fire conditions weather santa ana winds_00000000.png
southern california january strong winds low humidity fire conditions weather santa ana winds_00000000.png
Now playing
01:19
Fire weather prevalent across Southern California
PHOTO: CNN
Now playing
02:34
Blizzard, rain, and snow to hinder Central and Eastern US weekend weather
PHOTO: POOL
Now playing
00:48
Pence makes surprise visit to Capitol to thank National Guard
FBI Director Christopher Wray speaks during a virtual news conference at the Department of Justice on October 28, 2020 in Washington, DC.
FBI Director Christopher Wray speaks during a virtual news conference at the Department of Justice on October 28, 2020 in Washington, DC.
PHOTO: Sarah Silbiger/Getty Images
Now playing
03:47
FBI director speaks publicly for first time since Capitol riots
PHOTO: From Public Report / Jeremy Lee Quinn
Now playing
01:39
Video from inside Capitol raises questions for investigators
A man receives a dose of the Moderna coronavirus disease (COVID-19) vaccine at a vaccination site at South Bronx Educational Campus, in the Bronx New York on January 10, 2021. (Photo by Kena Betancur / AFP) (Photo by KENA BETANCUR/AFP via Getty Images)
A man receives a dose of the Moderna coronavirus disease (COVID-19) vaccine at a vaccination site at South Bronx Educational Campus, in the Bronx New York on January 10, 2021. (Photo by Kena Betancur / AFP) (Photo by KENA BETANCUR/AFP via Getty Images)
PHOTO: KENA BETANCUR/AFP/Getty Images
Now playing
02:25
Coronavirus cases surge as states struggle to vaccinate
(CNN) —  

Former Barcelona and Spain manager Luis Enrique has paid tribute to his nine-year-old daughter after she passed away from osteosarcoma – a form of bone cancer.

The 49-year-old released a statement on Twitter Thursday evening confirming Xana’s death and thanking hospital staff for their care over an “intense five months.”

“We will miss you lots but we will remember you every day of our lives, with the hope that in the future we’ll meet each other again,” read the statement.

“You’ll be the star that guides our family.”

The Spaniard, who stepped down from his role as Spain’s national boss in June to spend time with his family, thanked those who sent good wishes but asked for “discretion and understanding.”

Enrique celebrates Barcelona
Enrique celebrates Barcelona's Champions League victory with his daughter Xana in 2015.
PHOTO: Laurence Griffiths/Getty Images Europe/Getty Images

’Speechless’

The Spanish Football Federation (RFEF) led the tributes online, saying it “mourned the sad loss of little Xana.”

“We want to show our condolences to family and friends, joining us all today to their pain,” it tweeted.

A host of Enrique’s former players also paid their respects to young Xana, among them Barcelona superstar Lionel Messi.

“We are with you, all the strength of the world,” the Argentine wrote on Twitter.

Meanwhile, Spain and Manchester United goalkeeper David de Gea said he was “speechless,” while Enrique’s former club Barcelona offered “condolences and all our sympathy.”

Tennis legend Rafael Nadal also sent his condolence to the family. Nadal’s uncle Miguel Ángel Nadal is a former Barcelona and national teammate of Enrique.

“I am very sad and I cannot imagine the pain of the family. A huge hug to Luis Enrique and the whole family from a distance. A lot of strength and courage in these hard times,” he tweeted.

A host of clubs, including Manchester United, also paid their respects.

Enrique enjoyed a successful playing career, representing Spain on 62 occasions. He also won three Spanish La Liga titles, once with Real Madrid and twice with rivals Barcelona.

He continued such success as a coach, winning the Champions League during his time at the Nou Camp, in addition to two domestic titles and three Copa del Rey trophies.

Barcelona president Josep Maria Bartomeu expressed his sympathy, writing: “All of our support and compassion goes to Luis Enrique, his wife and all of his family at this particularly painful time.”