But one woman stood out -- 28-year-old JoAnn Morgan.
Morgan, who worked as an instrumentation controller for the mission, was the only woman allowed inside the firing room where NASA employees were locked during Apollo 11's historic lift off on July 16, 1969.
Morgan needed to be in the room to alert the test team if anything went wrong. But she had to get special permission to be there.
"My director of information systems called me and said, 'You're our best communicator. We're going to have you on the console,'" she said. "But later I found out he had to convince the center director Dr. Kurt Debus that it was going to be OK."
You can see never-seen-before footage of Morgan in CNN Films' documentary "Apollo 11." She inspired a generation of women -- but her path wasn't always an easy one.
No women's restrooms
As the first female engineer at Cape Canaveral, Morgan recalled being "immersed in a man's world where everybody around me were men."
That fact became quite apparent at certain times.
"A lot of the buildings I worked in didn't have ladies' restrooms," she said.
Just like the women in the movie "Hidden Figures," Morgan had to go to another building or use the men's room.
"Sometimes during tests, the guard was just great. He'd come over and say, 'You need a little break? I'll police the men's room.'"
Morgan said the guys tried not to notice. "If I had to go, I had to go!" she said with a laugh.
Obscene phone calls and 'come-ons'
Being a female also meant dealing with sexism and come-ons from time to time.
"When I first started in Blockhouse 34, the test supervisor came and literally hit me on the back. He said, 'We don't have women here.' And I thought, 'Uh oh.' So, I called my director ... and phone calls were made," she said. "That very same day, the big guy in charge of the Apollo program at the Kennedy Space Center came down ... and he said, 'JoAnn, you are welcome to work here. Don't worry about anything anybody says.'"
When Morgan first started working in the firing room, she also got some obscene phone calls.
"One time when one of them came through, I slammed the phone down. And one of the television operators from the station downstairs came up and he said, 'Is something wrong? Is something wrong?' And I said, 'Yeah.' He said, 'The look on your face. Has there been a death in the family?' I said, 'No, an obscene phone call.'"
"But I never let myself feel like an object. I was not going to be an object. I just had too much fearlessness in me to let that be any kind of deterrent."
Roy Tharpe sat next to Morgan in the firing room as the chief test support controller for Apollo 11.