Cuban workers walk along the new Venezuelan-Cuban oil refinery Camilo Cienfuegos 20 December, 2007 in Cienfuegos, some 280km east from Havana. Venezuelan President Hugo Chavez will inaugurate the refinery on Friday in the sidelines of the fourth summit of Petrocaribe, a Venezuelan initiative to provide oil to Caribbean neighbors at preferential prices. Chavez will head the summit with acting president Raul Castro. AFP PHOTO/ADALBERTO ROQUE (Photo credit should read ADALBERTO ROQUE/AFP/Getty Images)
ADALBERTO ROQUE/AFP/AFP/Getty Images
Cuban workers walk along the new Venezuelan-Cuban oil refinery Camilo Cienfuegos 20 December, 2007 in Cienfuegos, some 280km east from Havana. Venezuelan President Hugo Chavez will inaugurate the refinery on Friday in the sidelines of the fourth summit of Petrocaribe, a Venezuelan initiative to provide oil to Caribbean neighbors at preferential prices. Chavez will head the summit with acting president Raul Castro. AFP PHOTO/ADALBERTO ROQUE (Photo credit should read ADALBERTO ROQUE/AFP/Getty Images)
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TOPSHOT - Venezuelan President Nicolas Maduro holds a national flag during the closing of the campaign to elect a Constituent Assembly that would rewrite the constitution, in Caracas on July 27, 2017 on the second day of a 48-hour general strike called by the opposition. Venezuela's opposition called for a nationwide protest on Friday in outright defiance of a new government ban on demonstrations ahead of a controversial weekend election. "The regime declared we can't demonstrate... We will respond with the TAKING OF VENEZUELA tomorrow," the opposition coalition, the Democratic Unity Roundtable, said Thursday on its Twitter account. / AFP PHOTO / Federico PARRA (Photo credit should read FEDERICO PARRA/AFP/Getty Images)
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he Asahi Shimbun via Getty Images
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(CNN) —  

The Trump administration imposed sanctions on Venezuelan President Nicolas Maduro’s wife and three other members of his inner circle.

On Tuesday, the Treasury Department announced new sanctions against Cilia Adela Flores de Maduro, the former attorney general and President of the National Assembly.

Delcy Rodriguez, the executive vice president of Venezuela and Jorge Rodriguez, the minister of popular power for communication and information, and Vladimir Padrino, the defense minister also were also sanctioned by the US government.

“We are continuing to designate loyalists who enable Maduro to solidify his hold on the military and the government while the Venezuelan people suffer,” said Treasury Secretary Steven Mnuchin said in a statement.

The US has been putting pressure on Maduro’s inner circle to weaken his grip of power as the people of Venezuela continue to suffer under hyperinflation, food shortages and a decline in oil production.

“Venezuela is a very sad case and we want to see it fixed – what’s happening there is a human tragedy,” President Donald Trump told reporters in New York, ahead of his speech at the United Nations General Assembly.