Former President George Bush, center, waves as he leaves with cardiologist Mark Hausknecht, left, and Bush's family doctor Ben Orman, right, after a news conference at Methodist Hospital Friday, Feb. 25, 2000 in Houston. Bush spent Thursday night in a Florida hospital and was released Friday after being treated for atrial fibrillation. He returned to Houston Friday and was admitted to Methodist Hospital for further tests. (AP Photo/David J. Phillip)
David J. Phillip/AP
Former President George Bush, center, waves as he leaves with cardiologist Mark Hausknecht, left, and Bush's family doctor Ben Orman, right, after a news conference at Methodist Hospital Friday, Feb. 25, 2000 in Houston. Bush spent Thursday night in a Florida hospital and was released Friday after being treated for atrial fibrillation. He returned to Houston Friday and was admitted to Methodist Hospital for further tests. (AP Photo/David J. Phillip)
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(CNN) —  

There is a “high probability” a cardiologist who treated former President George H.W. Bush was targeted when he was fatally shot last week riding his bicycle to work, Houston’s police chief said Wednesday.

A sketch of a suspect in the death of Dr. Mark Hausknecht
Houston Police Department/Houston Police Department
A sketch of a suspect in the death of Dr. Mark Hausknecht

But Chief Art Acevedo emphasized that investigators are still not certain of the motive.

“There is a high probability the doctor was targeted,” the chief said in a tweet from Houston police.

The suspected gunman remains at large. In a brief interview, Acevedo said he is confident police will be able find the suspect and make an arrest in the death of Dr. Mark Hausknecht because there were several witnesses in the area at the time of Friday’s shooting.

Acevedo declined to say why he believed the cardiologist was likely targeted. The FBI’s Houston bureau is helping city police with the investigation.

Surveillance images could be key

Hausknecht, who worked at Houston Methodist Hospital, and the suspect were seen shortly before the shooting riding bicycles on South Main Street, police said. Surveillance footage shows the suspect following the physician as both pedaled north, police said.

This surveillance image shows a suspect in the shooting of Dr. Mark Hausknecht, police say.
Houston Police Department
This surveillance image shows a suspect in the shooting of Dr. Mark Hausknecht, police say.

Georgia Hsieh, the wife of the renowned cardiologist, said police told her that her husband was riding through a construction area when the gunman rode up in front of him and fired three shots while facing him.

Hausknecht, circled in green, was followed by a cyclist, in red, shortly before the shooting, police say.
Houston Police Department/Houston Police Department
Hausknecht, circled in green, was followed by a cyclist, in red, shortly before the shooting, police say.

A close-up surveillance image shows the suspect wearing a blue, short-sleeve polo shirt, a khaki or white cap, khaki shorts and an olive-green backpack, police say.

The suspect, circled in red, nears Hausknecht on the road.
Houston Police Department/Houston Police Department
The suspect, circled in red, nears Hausknecht on the road.

Other surveillance images show the suspect just behind Hausknecht as both head north on Main across West Holcombe Boulevard, police say. In the images posted on Twitter, police highlighted Hausknecht with a green circle and the suspect with a red circle.

The shooting happened moments after that crossing, one block away, police say.

CNN’s Jamiel Lynch, Darran Simon, Jason Hanna, Eric Levenson and Emanuella Grinberg contributed to this report.