Twins treated for genetic disorder in the womb

Corinna's twin boys -- Maarten, left, and Linus -- were the first humans to be treated for their genetic disorder while still inside the womb.

Story highlights

  • A genetic disorder that leads to underdeveloped sweat glands and teeth was treated in the womb
  • It's the first successful medical treatment of a human fetus for the underlying cause of a genetic disorder, experts say

(CNN)Corinna already had one child with a genetic disorder that left him unable to sweat or grow teeth normally.

The disorder -- X-linked hypohidrotic ectodermal dysplasia -- primarily affects boys and can result in overheating, which can be life-threatening in severe cases. It can also affect saliva and tear production.
Corinna and her husband, Tobias, who requested that CNN not use their last name for privacy reasons, discovered the genetic defect when their son was 2 years old and still had no teeth.
    "The hotter it is, the more water he needs to cool down his body temperature," Corinna, 40, who lives in Germany, wrote in an email. It's like "the engine of a car that runs without cooling water."
    Then, Corinna and Tobias found out that she was pregnant again -- with twin boys. Doctors confirmed that the twins carried the affected gene.