NEW YORK, NY - JUNE 16: Guests can stop at a kiosk an receive a mean-spirited nickname from a nickname generator at The Daily Show-produced 'Donald J. Trump Presidential Twitter Library,' June 16, 2017 in New York City. The parody library showcases President Trump's tweets through the years. (Photo by Drew Angerer/Getty Images)
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NEW YORK, NY - JUNE 16: Guests can stop at a kiosk an receive a mean-spirited nickname from a nickname generator at The Daily Show-produced 'Donald J. Trump Presidential Twitter Library,' June 16, 2017 in New York City. The parody library showcases President Trump's tweets through the years. (Photo by Drew Angerer/Getty Images)
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(CNN) —  

Senate Minority Leader Chuck Schumer invoked first lady Melania Trump’s “Be Best” initiative in a response to President Donald Trump’s tweet Thursday morning calling him “Cryin’ Chuck.”

“Senator Cryin’ Chuck Schumer fought hard against the Bad Iran Deal, even going at it with President Obama, & then Voted AGAINST it!” Trump wrote on Twitter Thursday morning. “Now he says I should not have terminated the deal - but he doesn’t really believe that!”

“#BeBest” the New York Democrat responded, referencing Melania Trump’s newly announced initiative, which encourages children to use the internet in positive ways.

The program, which Mrs. Trump unveiled on Monday includes efforts to tamper down cyberbullying and negativity, despite her husband often using Twitter for name-calling and attacks.

During the campaign and his presidency, Trump has used nicknames for his critics and opponents, such as “Lyin’ Ted” Cruz, “Little Marco” Rubio or “Sloppy Steve” Bannon.

“Cryin’ Chuck Schumer” is a nickname Trump has attacked Schumer with before, although the two have also connected over their shared status as New Yorkers.

Last year, House leader Nancy Pelosi quipped that a deal struck with Trump came about because Schumer “could speak New York to the President.”

In September, Schumer was caught on a hot-mic saying Trump “likes us. He likes me anyway.”

The Schumer-Trump relationship, however, appeared to sour as they attempted to negotiate a deal on immigration and border security in January.