NEW YORK, NY - MARCH 30: New York State Attorney General Eric Schneiderman speaks at a press conference announcing new guidelines and testing standards that GNC will adhere to for their herbal supplements and extracts on March 30, 2015 in New York City. After testing hermal supplements and extracts from various retailers last year and finding false ingredients in their products, the attorney general's office subpoenaed GNC and other providers to further investigate their products. (Photo by Andrew Burton/Getty Images)
Andrew Burton/Getty Images
NEW YORK, NY - MARCH 30: New York State Attorney General Eric Schneiderman speaks at a press conference announcing new guidelines and testing standards that GNC will adhere to for their herbal supplements and extracts on March 30, 2015 in New York City. After testing hermal supplements and extracts from various retailers last year and finding false ingredients in their products, the attorney general's office subpoenaed GNC and other providers to further investigate their products. (Photo by Andrew Burton/Getty Images)
Now playing
02:36
NY attorney general resigns over allegations
Employees work on computers inside the FEMA Command Center at Federal Emergency Management Agency Headquarters in Washington, DC, August 4, 2017. / AFP PHOTO / SAUL LOEB        (Photo credit should read SAUL LOEB/AFP/Getty Images)
SAUL LOEB/AFP/Getty Images/FILE
Employees work on computers inside the FEMA Command Center at Federal Emergency Management Agency Headquarters in Washington, DC, August 4, 2017. / AFP PHOTO / SAUL LOEB (Photo credit should read SAUL LOEB/AFP/Getty Images)
Now playing
02:54
Former FEMA head accused of sexual misconduct
Now playing
01:19
Women share #MeToo stories in campaign videos
New York Attorney General Eric Schneiderman speaks during a press conference at the office of the New York Attorney General, September 13, 2016 in New York City.
Drew Angerer/Getty Images
New York Attorney General Eric Schneiderman speaks during a press conference at the office of the New York Attorney General, September 13, 2016 in New York City.
Now playing
01:48
Attorney General Eric Schneiderman resigns
Getty Images/CNNMoney
Now playing
00:58
Watch: Schneiderman rails against Weinstein
NEW YORK, NY - JANUARY 27:  Lisa Loeb, Blake Farenthold and guest at the 60th Annual GRAMMY Awards - GRAMMY Congressional Briefing at Brooks Atkinson Theatre on January 27, 2018 in New York City.  (Photo by Eugene Gologursky/Getty Images for NARAS)
Eugene Gologursky/Getty Images
NEW YORK, NY - JANUARY 27: Lisa Loeb, Blake Farenthold and guest at the 60th Annual GRAMMY Awards - GRAMMY Congressional Briefing at Brooks Atkinson Theatre on January 27, 2018 in New York City. (Photo by Eugene Gologursky/Getty Images for NARAS)
Now playing
00:55
Rep. Blake Farenthold resigns from Congress
LOS ANGELES, CA - DECEMBER 15:  Hillary Clinton speaks onstage at LA Promise Fund's "Girls Build Leadership Summit" at Los Angeles Convention Center on December 15, 2017 in Los Angeles, California.  (Photo by Alberto E. Rodriguez/Getty Images)
Alberto E. Rodriguez/Getty Images North America/Getty Images
LOS ANGELES, CA - DECEMBER 15: Hillary Clinton speaks onstage at LA Promise Fund's "Girls Build Leadership Summit" at Los Angeles Convention Center on December 15, 2017 in Los Angeles, California. (Photo by Alberto E. Rodriguez/Getty Images)
Now playing
02:19
NYT: Clinton blocked firing of adviser accused of harassment
Jessica Leeds-2 12-6-17
CNN
Jessica Leeds-2 12-6-17
Now playing
01:01
Trump accuser: He groped me because of boredom
UNITED STATES - MAY 25: Rep. Pat Meehan, R-Pa., talks on his phone as he walks down the House steps following votes in the Capitol on Wednesday, May 25, 2016. (Photo By Bill Clark/CQ Roll Call)
Bill Clark/CQ-Roll Call Group/Getty Images/FILE
UNITED STATES - MAY 25: Rep. Pat Meehan, R-Pa., talks on his phone as he walks down the House steps following votes in the Capitol on Wednesday, May 25, 2016. (Photo By Bill Clark/CQ Roll Call)
Now playing
01:53
Rep. Meehan says ex-aide is his soul mate
Casino mogul Steve Wynn during a news conference in Medford, Mass., Tuesday, March 15, 2016.
Charles Krupa/AP
Casino mogul Steve Wynn during a news conference in Medford, Mass., Tuesday, March 15, 2016.
Now playing
01:58
Steve Wynn steps down from RNC
NBC's "Today"
Now playing
01:26
Accuser: Conyers requested sexual favors
allegations against Al Franken orig me_00000000.jpg
allegations against Al Franken orig me_00000000.jpg
Now playing
02:34
The allegations against Al Franken (2017)
CNN
Now playing
00:46
Moore spokeswoman brings up anchor's baby
WASHINGTON, DC - OCTOBER 13: Roy Moore, GOP Senate candidate and former chief justice on the Alabama Supreme Court speaks during the annual Family Research Council's Values Voter Summit at the Omni Shorham Hotel on October 13, 2017 in Washington, DC.  (Photo by Mark Wilson/Getty Images)
Mark Wilson/Getty Images North America/Getty Images
WASHINGTON, DC - OCTOBER 13: Roy Moore, GOP Senate candidate and former chief justice on the Alabama Supreme Court speaks during the annual Family Research Council's Values Voter Summit at the Omni Shorham Hotel on October 13, 2017 in Washington, DC. (Photo by Mark Wilson/Getty Images)
Now playing
01:15
Roy Moore: Allegations are completely false
Sarah Sanders WHPB 11-16-17
CNN
Sarah Sanders WHPB 11-16-17
Now playing
00:49
WH on Moore: It's up to the people of Alabama
The Capitol dome is seen early on the morning of the dress rehearsal for the inauguration of President-elect Donald Trump, January 15, 2017 in Washington, DC.
AFP/Getty Images
The Capitol dome is seen early on the morning of the dress rehearsal for the inauguration of President-elect Donald Trump, January 15, 2017 in Washington, DC.
Now playing
01:52
Women of Congress share #MeToo stories
Washington CNN —  

New York Attorney General Eric Schneiderman has resigned, following a report on allegations of assault by multiple women in The New Yorker.

“It’s been my great honor and privilege to serve as Attorney General for the people of the State of New York. In the last several hours, serious allegations, which I strongly contest, have been made against me,” Schneiderman said in a statement. “While these allegations are unrelated to my professional conduct or the operations of the office, they will effectively prevent me from leading the office’s work at this critical time. I therefore resign my office, effective at the close of business on May 8, 2018.”

Shortly after he announced his resignation, the Manhattan District Attorney’s office said they had opened an investigation into the allegations against Schneiderman, a spokesman told CNN.

Schneiderman’s swift resignation, which came just hours after The New Yorker published its report, is a shocking fall from grace for a once rising star in Democratic politics. Schneiderman had cast himself as a fierce opponent and critic of President Donald Trump.

Schneiderman has also been a vocal proponent of the #MeToo movement, bringing legal action in New York against film producer Harvey Weinstein, who has been accused of sexually assaulting women.

New York Gov. Andrew Cuomo had called for Schneiderman’s resignation earlier Monday.

“No one is above the law, including New York’s top legal officer,” Cuomo said in a statement. “I will be asking an appropriate New York District Attorney to commence an immediate investigation, and proceed as the facts merit.”

“My personal opinion is that, given the damning pattern of facts and corroboration laid out in the article, I do not believe it is possible for Eric Schneiderman to continue to serve as Attorney General, and for the good of the office, he should resign,” he added.

On Monday, The New Yorker magazine reported the allegations of four women who accused Schneiderman of physical violence against them.

Two of the women, Michelle Manning Barish and Tanya Selvaratnam, spoke on the record to the magazine, saying they had been romantically involved with Schneiderman but that the violence was nonconsensual, and which The New Yorker described as occurring “often after drinking, frequently in bed and never with their consent.”

According to The New Yorker, Manning Barish and Selvaratnam said he had hit and choked them, and that they later sought medical attention because of it. Selvaratnam also alleged that Schneiderman threatened to tap her phone, among other threats.

Both women alleged that the incidents often occurred after Schneiderman had been drinking.

“I could not remain silent and encourage other women to be brave for me,” Manning Barish posted on Facebook. “I could not leave my sisters who had been harmed hanging-discredited-when I knew the truth.”

In a statement forwarded to CNN through a friend, Selvaratnam said that after finding out other women had accused Schneiderman of abuse, she wondered who was next.

“So I chose to come forward both to protect women who might enter into a relationship with him in the future but also to raise awareness around the issues of intimate partner violence,” her statement read.

Schneiderman, a Democrat, tweeted a statement on Monday evening, writing that nonconsensual sex “is a line I would not cross.”

“In the privacy of intimate relationships, I have engaged in role-playing and other consensual sexual activity. I have not assaulted anyone. I have never engaged in non-consensual sex, which is a line I would not cross,” the tweet reads.

Jennifer Cunningham, Schneiderman’s ex-wife, came to his defense Monday evening and said in a statement that the allegations “are completely inconsistent with the man I know.”

“I’ve known Eric for nearly 35 years as a husband, father and friend. These allegations are completely inconsistent with the man I know, who has always been someone of the highest character, outstanding values and a loving father. I find it impossible to believe these allegations are true,” Cunningham said.

The New York Police Department said in a statement that it had no complaints against Schneiderman but that if it receives any “it will investigate them thoroughly.”

Democratic Sen. Kirsten Gillibrand of New York earlier Monday evening had echoed Cuomo’s calls for Schneiderman to step down.

“The violent actions described by multiple women in this story are abhorrent,” Gillibrand said in a statement. “Based on this extensive and serious reporting, I do not believe that Eric Schneiderman should continue to serve as Attorney General. There should be a full and immediate investigation into these credible allegations.”

CNN had reached out to Schneiderman, who is not married, for comment and was given a copy of his tweet.

Two more women, who are unnamed, also accuse Schneiderman of physical abuse in the news report, including one woman who is characterized by The New Yorker as “an attorney who has held prominent positions in the New York legal community” and asked to remain anonymous. The reportedly prominent lawyer said that when she rejected Schneiderman, he slapped her so forcefully a mark was still visible the following day, according to The New Yorker.

Following the report outlining allegations against Schneiderman, Trump counselor to the President Kellyanne Conway shared a tweet of Schneiderman’s from October 2017 where he called out the Trump administration, saying: “No one is above the law, and I’ll continue to remind President Trump and his administration of that fact everyday.”

To this, Conway replied in her own tweet: “Gotcha.”

CNN’s Rob Frehse and Ellie Kaufman contributed to this report.