Out of the total team of 24 members, five boxers and three weightlifters have disappeared over the space of three days, the statement said.
They left in waves, with three going missing on the night of April 8, another two vanishing on April 9 before the remaining group left at night on April 10. Two of the eight left without competing.
Team attache Simon Molombe said he did not expect them to return. "I don't think they will be back," Cameroon's Molombe told CNN Sport, confirming their disappearance had been reported to Australian police.
- Weight lifter Arcangeline Fouodji Sonkbou
- Boxer Arsene Fokou
- Boxer Christelle Ndiang
- Boxer Christian Ndzie Tchoyi
- Weight lifter Olivier Hercales Matam Matam
- Weight lifter Petit David Minkoumba
- Boxer Simplice Fotsala
- Boxer Ulrich Yombo
"Most of them departed in the night when everyone was sleeping. Nobody knows the direction they have gone," Cameroon team spokesman Simon Lyonga told CNN affiliate Seven News.
According to Seven, the athletes' visa requirements expire on May 15, allowing them to spend another month legally in Australia.
David Grevemberg, Commonwealth Games Federation CEO, said the situation remained an issue for the Cameroon team until the athletes breached their visas.
"It is obviously disappointing that some of the athletes who have come didn't compete when scheduled to compete," he said at a press conference Wednesday.
"I think it is also important to remember that these athletes are guests here in Australia and are still within their visas and have the right to travel freely."
The 2018 Games are currently underway in the Gold Coast in the Australian State of Queensland. They're expected to conclude on Sunday April 15.
More than 4,500 athletes from 71 countries will take part during the course of the games, which began on April 5, competing for a total of 275 gold medals
It is not the first time athletes have disappeared during major sporting events.
During the 2006 Commonwealth Games in Melbourne 25 competitors went missing, while 26 disappeared during the 2002 Games in Manchester.
At London 2012, seven Cameroon athletes disappeared during the Olympics.
Home to 200 different linguistic groups, French Cameroon gained independence from France in 1960
as the Republic of Cameroon.
Last year there were violent clashes as protestors took to the streets in Cameroon's Anglophone regions calling for symbolic independence from the country's French-speaking majority.
Peter Beattie, chairman of the local organizing committee, said it was not a surprise.
"Frankly, the bottom line is it happens regularly within Australia, there is a mechanism in place to deal with it and I don't get too excited by this," he told reporters Wednesday.
In January, Australia's Home Affairs Minister Peter Dutton
warned athletes who were planning to attend the games they needed to follow the country's laws.
"Our message to the half a percent of people who might think that they can overstay a visa or not act within the conditions of their visa is that Australia has very tough laws and they need to abide by the law," he said in Canberra on January 30.