"She wanted to help people, she wanted to help women and children ... have more education and more rights," sister Mayana Akbari said.
So several years ago, Lisa left for Afghanistan from the United States, working for nonprofits and for the Department of Defense, her sister said.
"She would always talk about her adventures -- how the people are, how hospitable and nice they were to her," Mayana said. "She loved the food. She loved the people."
But on Sunday, shortly after Mayana made her sister a scrapbook as a Christmas gift, her father got the call from the U.S. Embassy in Kabul.
"He just dropped to the ground and started crying," said Mayana, who didn't witness her father's reaction but was told about it later by him.
Lisa Akbari, 35, was shot to death as she was leaving the gym at her apartment complex. Afghan police have arrested a mullah suspected of killing her.
Possible terror group ties
Kabul District Police Chief Fraidoon Obaidi said the arrested mullah was injured, but he declined to say how or why.
He said investigators have seized documents from the mullah's home that allegedly show he has links to terrorist groups, but the chief did not specify which groups.
Police did not identify the mullah or say what charges he may face, but said he is being interrogated.
The mullah lived in Akbari's housing complex, Afghanistan's TOLO News agency reported.
While the motive for the killing has not been determined, Mayana Akbari suspects her sister's recent conversion to Christianity and efforts to evangelize may have played a role.
"We're not sure if that's the exact reason for her death," Mayana said. But "she wanted to spread the word. I guess she said the words to the wrong person."
More Americans killed
About 34 miles away from where Akbari was shot, six NATO service members were killed
in a motorcycle bomb attack Monday in Bagram, Afghanistan, military officials told CNN.
All six were American, U.S. Defense Secretary Ash Carter said.
The area is close to the U.S. base in the Bagram district of northern Parwan province.
Mayana Akbari said she is grief-stricken not only by the loss of her sister, but also by the loss of the six service members.
"My condolences go out to the other families, because I know how they feel," she said. "To lose those close to them right in the holiday season, it's just devastating."
Back to her roots
Lisa Akbari wanted to go to Afghanistan not just to help women and children, but also to learn more about her heritage. Her father is from Afghanistan, and her mother is Irish-American.
"She was always wanting to learn more about Dad's culture," her sister said.
One of the nonprofits she worked for was World Vision, the Christian humanitarian group said.
"World Vision has lost a valued colleague. Our sorrow and confusion at this time are little compared to what Lisa's family must be feeling," said Jim Alexander, national director of World Vision Afghanistan.
Lisa was also a prankster, so much so that when Mayana got the call that her sister was killed, she wondered if it was an elaborate prank.
But after the harsh reality set it, Mayana is left to grapple with the loss of a sister and a mother figure.
"She's 35, and I'm only 20. She practically raised me since I was a baby," Mayana said.
"She was a selfless, caring person," the sister said. "She cares about people she hardly even knows -- the homeless, anyone. ... She left so many broken hearts. "