Dropping just 5% to 10% of your body weight can improve your overall health and reduce your risk for heart disease and diabetes.
But shedding unwanted pounds can also have less-obvious effects, and not always for the better, says Dr. Adam Tsai, a physician at Kaiser Permanente Colorado and a spokesperson for the Obesity Society.
Here are nine things -- the good and the bad -- that you don't normally hear about losing weight:
1. Your energy levels will skyrocket
A big energy boost is often the first thing people notice when they start dropping weight. Why?
When you're carrying around fewer pounds, you use less energy to simply go about your day, says Tsai.
Weight loss also improves oxygen efficiency, so you won't find yourself out of breath so easily when climbing stairs or hustling to catch the bus.
2. Your memory may improve
In a 2013 Swedish study, older women scored better on memory tests after six months of following a weight-loss plan.
Brain scans showed more activity during the encoding process, when memories are formed, and less activity during memory retrieval, suggesting greater recall efficiency.
"The altered brain activity after weight loss suggests that the brain becomes more active while storing new memories and therefore needs fewer brain resources to recollect stored information," said study author Dr. Andreas Pettersson in a news release.
Previous research has also linked obesity to poor memory, especially in pear-shaped women who carry extra pounds around their hips.
3. Your relationship will be tested
Losing weight can make you feel sexier, but your slimmed-down body -- and that newfound confidence -- won't necessarily strengthen your bond with your spouse.
In a 2013 study from North Carolina State University, researchers found that although dropping 60 pounds or more in two years or less usually improved couples' relationships, occasionally a dieter's partner felt jealous or threatened.
Why? Your body transformation may force your significant other to consider his or her own health choices, says Dr. Gail Saltz, Health.com's contributing psychology editor.
Another problem: Your partner may worry about how your personality might change.
"You feeling great, sexy, or confident could shift the balance of the relationship," Saltz says. "They fear losing the identity of the more confident one or losing the upper hand."
Many of these challenges could apply to friendships, too.
4. Your risk of cancer will be lower
You know that smoking, sun exposure and radiation can cause cancer, but obesity has been linked to several types of cancers as well, says Tsai.
Being overweight causes inflammation that triggers cell changes within the body.
Dangerous levels of inflammation can be lowered, however, by losing just 5% of your body weight, according to a 2012 study on postmenopausal women published in the journal Cancer Research. And a 2014 study published in Obesity Research found that morbidly obese men who underwent bariatric surgery reduced their cancer risk over the following years to roughly that of normal-weight people.
5. If you were depressed before, that may not change
Does being overweight make you depressed or does being depressed lead to weight gain?
It's not always possible to tell what comes first, says Tsai.
And while most people feel happier after they've lost weight, it's not a cure-all. "For a smaller percentage of people, mood will not improve even after they lose 100 pounds," he says.
That may be because weight loss doesn't address any underlying problems you may have, says Saltz.
6. Foods might taste differently
Losing a lot of weight in a small amount of time might alter your taste buds.
A recent Stanford University study revealed that after bariatric surgery, 87% of patients reported a change in their sense of taste.
About half said food tasted sharper, while the other half said food tasted duller.
The upshot: Those who tasted food less intensely after surgery lost 20% more weight over three months than those who said foods tasted stronger.
The study authors say more research is needed to determine why the change in taste occurs, but another recent study did have similar findings.
The study, from Leicester Royal Infirmary in the United Kingdom, found that three quarters of weight loss surgery patients developed a dislike for certain foods after their operations, most often meat and dairy products.
7. Working out will be more fun
When you're carrying around extra pounds, exercising can make your joints hurt and lungs burn more than someone who's at normal weight, says Tsai.
Once you start to slim down, exercise will start to feel less like a chore and more like the fun, energizing experience that it should be. Plus, being lighter can also make you faster and stronger.
Take running, for example: It's generally believed that for every pound lost, an athlete can shave two seconds off the time it takes to run a mile.
8. Your bones may change
Ever heard that losing weight weakens your bones?
While it's true that weight loss is associated with bone loss, it's only a big concern if you become underweight or follow an unhealthy diet, and the National Osteoporosis Foundation says that the benefits of weight loss usually outweigh the risks.
Extra weight can make your bones stronger (they have to be, to carry the extra pounds) but it also damages joints. And new research suggests that visceral fat around the belly is particularly bad for bones, for both men and women.
Losing weight can help, as well as reduce arthritis symptoms, according to a 2013 review published in the Journal of the American Academy of Orthopedic Surgeons.
9. You'll probably spend less on health care
Normal-weight people spend less money on medical bills and expenses than their overweight peers, according to a 2009 study published in the journal Health Affairs.
Specifically, researchers found obese people spent $1,429 more -- that's 42% higher -- than their normal-weight peers, most of which went toward prescription medications needed to manage chronic conditions. And a 2014 report on Michigan residents found that annual health care costs for people who were extremely obese were a whopping 90% higher than those of normal-weight individuals.
In related sad-but-true news, you might notice something else when you lose weight, as well: Doctors (whose bias against obese patients has been well-documented) might treat you better, too.