(CNN)White House Chief of Staff Denis McDonough on how the sudden power shifts in the Middle East will impact the U.S. fight against ISIS and Al Qaeda.
With relations between President Obama and Israeli P.M. Benjamin Netanyahu on ice, can the U.S. still trust its closest ally in the region? House Intelligence Committee member, Rep. Adam Schiff and former Republican presidential candidate and U.S. ambassador Jon Huntsman weigh in.
The first major presidential cattle call of 2016 happens this weekend in Iowa. Former and possible future Republican presidential candidate Rick Santorum joins us.
Why is "American Sniper" hitting a nerve in the nation's culture debate? We'll hear from two Iraq war veterans, Rep. Adam Kinzinger and Rep. Ruben Gallego.
Plus, on the 50th anniversary of Winston Churchill's death, his grandson, Sir Nicholas Soames reflects on his grandfather's legacy.
Michael Smerconish hosts State of the Union on Sunday at 9am and Noon ET on CNN.