Warren and his wife, Kay, are interviewed by CNN's Piers Morgan in Rancho Santa Margarita, California, on Monday, September 16. The couple has been outspoken about the plague of gun violence in the United States, especially since their son, Matthew, took his own life. In reference to that loss, Warren states that, "in spite of America's best doctors, meds, counselors and prayers for healing, the torture of mental illness never subsided."
A woman flips through Warren's "The Purpose Driven Live" in a Christian bookstore in Atlanta in 2005. Interest in the book surged that year after Ashley Smith read portions of the book to murder suspect Brian Nichols as he held her captive in her suburban Atlanta apartment and persuaded him to surrender. Robin Nelson/ZUMAPRESS
Warren speaks to his congregation at Saddleback Church in 2005. Rob DeLorenzo/ZUMAPREss
Rick Warren and his wife, Kay Warren, open the 2005 HIV/AIDS Conference, "Disturbing Voices," in 2005 at the Saddleback Church. Damian Dovarganes/AP
Warren discusses religion and faith with Sam Harris, well-known atheist and author of the book "End of Faith," and Newsweek editor Jon Meachum on March 21, 2007. Charles Ommanney/Getty Images
Hillary Clinton, right, then a Democratic presidential candidate, views an AIDS exhibit at the third annual Global Summit on AIDS and the Church at Warren's Saddleback Valley Community Church on November 29, 2007. All the presidential candidates were invited to attend the summit, but Clinton was the only one to attend in person. Chris Carlson/Pool/Getty Images
Warren speaks during the White House Roundtable on Faith-Based and Community Solutions to Combat HIV/AIDS in Washington on December 12, 2007. The theme of the roundtable was to show that religious organizations are a key component in the global fight against HIV/AIDS. Chip Somodevilla/Getty Images
Presidential candidates Sens. John McCain and Barack Obama join Warren onstage at the Saddleback Civil Forum on the Presidency at Saddleback Church on August 16, 2008. Jonathan Alcorn/Bloomberg News/Getty Images
Warren, right, attends the Clinton Global Initiative on September 26, 2008, in New York with Steve Gunderson, left, president and CEO of the Council on Foundations, and Muhammad Yunus, the founder and managing director of the Grameen Bank. The three-day event aimed to bring together global leaders to develop and implement workable solutions to some of the world's most pressing challenges. STAN HONDA/AFP/Getty Images
Hundreds of protesters gather outside Warren's Saddleback Church on October 19, 2008, after Warren came out in support of California's Proposition 8, denying same-sex couples the right to marry.
Warren presents President George W. Bush with the International Medal of P.E.A.C.E, as Laura Bush looks on, during the Saddleback Civil Forum on Global Health at the Newseum in Washington on December 1, 2008. The award was in recognition of an initiative to provide funding for treatment for 2 million people with HIV/AIDS by the end of 2008. The acronym P.E.A.C.E. stands for: Promote reconciliation. Equip servant leaders, Assist the poor, Care for the sick, Educate the next generation. Mark Wilson/Getty Images
Warren poses with a copy of his book "The Purpose of Christmas" during a book-signing in 2008 in New York. Sharkpixs/ZUMA Press
Warren delivers a speech to the convention of the Muslim Public Affairs Council in Long Beach, California, in 2008. Under fire for opposing same-sex marriage, Warren said during the speech that he loves Muslims, people of other religions, Republicans and Democrats, and that he also loves "gays and straights." Hector Mata/AP
Warren delivers the Martin Luther King Jr. Day keynote address at Ebenezer Baptist Church in Atlanta on January 19, 2009. John Bazemore/AP
Warren gives the invocation as President-elect Barack Obama and Michelle Obama bow their heads during swearing-in ceremonies at the U.S. Capitol on January 20, 2009. Ron Edmonds/AP
"Purpose Driven Connection," a subscription membership magazine produced by Warren with publisher Reader's Digest Association Inc., officially launched on January 26, 2009. PRNewsFoto/The Readerís Digest Association Inc./AP
Nick Jonas of the Jonas Brothers embraces Warren after a short performance with his brothers during the church's 30th anniversary Easter services at Angel Stadium in Anaheim, California, on April 4, 2010. Mindy Schauer/The Orange County Register/ZUMA press
Former British Prime Minister Tony Blair and Warren fist-bump during the "Civil Forum on Peace in a Globalized Economy" at Saddleback Church on March 6, 2011. Paul Bersebach/Orange County Register/AP
Warren and his wife, Kay, pose with a crowd during the grand opening of the P.E.A.C.E Center at Saddleback Church on December 12, 2011. The center will provide services for low-income families including medical help, counseling, tutoring and food. Carlos Delgado/The Orange County Register/ZUMA PRESS
Warren's 27-year-old son, Matthew Warren, committed suicide on April 6, after struggling with mental illness and deep depression, according to a statement from the Saddleback Valley Community Church. Saddleback Valley Community Church/AP
Warren attends the "Rally the People of Kayonza" in Kayonza, Rwanda, on August 27. courtesy saddleback church
Pastor Rick Warren gives a sermon on Saturday, September 14, at Saddleback Church in Lakewood, California.
Warren delivers a sermon at Saddleback Church on September 14. Adam Rose
Rick and Kay Warren share a touch during the CNN interview on September 16. It was their first time speaking to the media about their son's death.