At least 78 people are killed and 180 wounded, police say
Attack hit a Shiite Hazara community
Pakistan's prime minister and president condemn the attack
A blast targeting Shiites in a busy Pakistani marketplace killed at least 78 people on Saturday, police told CNN.
The attack in the southwestern Pakistan city of Quetta left at least 180 people wounded.
The explosives were packed into a parked water tanker and were remotely detonated, said Mir Zubair Mehmood, a senior police official in Quetta.
Pakistan, which is overwhelmingly Sunni, has been plagued by sectarian strife and attacks for years.
Last month, two deadly suicide bombings in a predominantly Shiite neighborhood of Quetta known as Alamdar Road killed 85 Shiite Muslims.
President Asif Ali Zardari and Prime Minister Raja Pervez Ashraf strongly condemned the bombing and vowed to go after the militants.
Earlier this year, a wave of attacks in Quetta left 87 people dead in the Shiite community.