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Tick spit study may stop sickness
Web posted at: 11:37 a.m. EDT (1537 GMT) In this story: From Correspondent Ann KellanNORTH KINGSTON, Rhode Island (CNN) -- It's tick season and if just the thought of these tiny, blood-sucking, disease-spreading parasites gives you the creeps, stop reading right now. This story is about scientists who collect ticks and analyze their saliva -- tick spit -- hoping to learn how to stop the spread of infection.
Professor Thomas Mather leads a team of scientists at the University of Rhode Island who do this odd-sounding but potentially valuable research. The work, he told CNN, could lead to useful new drugs for fighting Lyme disease and other infections transmitted by ticks. (
As a tick sucks blood with its mean-looking pinchers, it also spits small amounts of saliva into its host, explains university researcher Nathan Miller. (
It's usually when a young tick sucks blood from a rodent that it picks up the disease-causing microorganisms that the tick will inadvertently spit into its next host, which could be a pet or a human. According to researchers, some mysterious compound in tick spit prevents the host's natural defenses from fighting the infectious organisms.
If researchers could identify that compound, says Miller, they might find a way to counteract it with a vaccine. (
You've been bitten, but don't know itResearchers also want to find the numbing agents in tick spit that allows the parasite to latch onto a host's skin without being detected. "If you felt it as soon as it bit you, you would whack it off," says Mather. "But (the numbing agent) makes it so you can't feel it."
In effect, says Mather, the saliva contains a pain killer that's essential during a tick's three- to five-day feeding period. ( That pain killer could lead to a useful medicine for humans. Researchers also want to isolate the anti-coagulant properties in tick spit that keep blood flowing when normally it would clot. Anti-coagulants are used to treat people who have blood clots or during blood transfusions. Researchers are still years away from applying what they're learning about tick spit. In the meantime, they advise, check yourself and your pets thoroughly if you're in areas known to harbor ticks. You have about 24 hours once a tick latches on before it potentially could start spitting out those harmful microorganisms.
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