Plants could yield anti-AIDS, cancer medicine
Botanical garden plays key role in medicinal
development
An expanded Web version of segments seen on CNN
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June 26, 1997
Web posted at: 5:15 p.m. EDT (2115 GMT)
ST. LOUIS, Missouri (CNN) -- A botanical garden in urban St.
Louis provides more than an aesthetic environment for plant
life. It's also fertile ground for breakthrough research
that could yield anti-cancer and anti-AIDS medicines.
For more than 10 years, botanists at Missouri Botanical
Garden have worked with pharmaceutical researchers in the
fight against human disease, collecting more than 25,000
plant samples for screening.
The garden's mission, according to its Web site, is "to
discover and share knowledge about plants and their
environment, in order to preserve and enrich life."
Many of the 56 botanists on staff have traveled to tropical
Africa and Madagascar in search of exotic plant life that
could be used for medicinal purposes. Samples of the
tropical plants are brought back to the garden in Missouri,
where researchers catalog the plants and identify which ones
are unfamiliar.
The promising plant samples are then shipped to medical
experts at the National Cancer Institute, who begin searching
for active pharmacological agents that might lead to a cancer
or AIDS treatments.
About one quarter of all prescription pharmaceuticals contain
at least one plant-derived ingredient.
Spurring medical advances
The botanical garden's work is part of a program called
Natural Products Research. Dr. James Miller of the Missouri
Botanical Garden says the research has helped uncover new
information about various plants and spurred medical
advances.
For example, Miller said, two of the most powerful
anti-cancer drugs come from a type of periwinkle.
He also said a different plant being researched
has yielded an anti-HIV and an anti-AIDS compound.
| Dr. James Miller... |
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"At the moment, it looks unlikely that this is going to
directly develop into an anti-AIDS medicine," he said.
"However, the possibility still exists today that we can
tinker with the chemical structure and that this will be a
lead molecule."
The Missouri Botanical Garden, founded in the early 19th
century and one of the nation's oldest botanical gardens,
covers 79 acres in a residential area of St. Louis. The
garden displays the tropical plants as part of its permanent
collection, where nearly 5 million plant species have been
catalogued and preserved.
Related sites:
Note: Pages will open in a new browser window
- Missouri Botanical Garden - View detailed information about the garden, ranging from
virtual tours of plants in bloom to research information.
- National Cancer Institute - The National Cancer Institute coordinates the National Cancer Program, which conducts and supports research, training, health
information dissemination, and other programs with respect to the cause, diagnosis, prevention, and treatment of cancer,
rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients.
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All Rights Reserved.