Some children outgrow temporal lobe seizures, but this is less likely if brain scans show a defect or scar where the seizures are originating. The defect or scar makes these seizures more difficult to control with medications, but it can also make the person a candidate for surgery.
Medications
Numerous medications are available to treat seizures, including:
- Carbamazepine (Tegretol)
- Phenytoin (Dilantin)
- Valproic acid (Depakene)
- Oxcarbazepine (Trileptal)
- Lamotrigine (Lamictal)
- Gabapentin (Neurontin)
- Topiramate (Topamax)
- Phenobarbital
- Zonisamide (Zonegran)
- Levetiracetam (Keppra)
- Tiagabine (Gabitril)
- Pregabalin (Lyrica)
- Felbamate (Felbatol)
However, many people don't achieve seizure control with medications alone. Possible side effects of anti-seizure medications include fatigue and dizziness.
Surgery
Surgery to remove the portion of the temporal lobe that's causing the seizures is often effective. Success rates range between about 65 percent to as high as 90 percent, depending on the cause of the temporal lobe seizures. Surgery is rarely an option if your seizures originate from a region of the brain that contains vital brain functions, and in cases where the seizures come from more than one area.
Before surgery, you'll need a comprehensive evaluation, with magnetic resonance imaging scans of your brain and, usually, observation of your seizures in a hospital-based monitoring unit using video recordings and EEG.
Researchers have been investigating the use of radiosurgery, which uses a gamma knife to deliver a precise dose of radiation to the damaged portion of the brain. This procedure is still considered experimental and the anti-seizure effects as well as the side effects aren't immediately apparent after the procedure, but instead become evident over time.
Although many people continue to need some medication to help prevent seizures after surgery, you may be able to take fewer drugs and reduce your dosages. In some cases, surgery for epilepsy can cause complications, such as permanently altering your cognitive abilities. Talk to your surgeon about his or her experience, success rates and complication rates with the procedure you're considering. You may also want to request a second opinion before undergoing surgery.
Vagus nerve stimulation
A device called a vagus nerve stimulator may be an option if medications are ineffective or cause serious side effects. The stimulator is implanted into your chest under the collarbone. Wires from the stimulator are attached to the vagus nerve in your neck. The device turns on and off according to an adjustable program, and can be activated with a magnet.
Pregnancy and seizures
Women who experience seizures can have healthy pregnancies. However, preconception planning is even more important for women who have seizures than it is for other women. By letting your doctor know that pregnancy is your goal, you can try to lower your seizure medication prior to pregnancy, and switch medications if necessary. The American Academy of Neurology recommends that women avoid using valproate during pregnancy because of risks to the baby. If your seizures can't be well-controlled with any other medication, discuss the potential risks with your doctor.
Contraception and anti-seizure medications
It's also important to know that some anti-seizure medications can alter the effectiveness of oral contraceptive (birth control) medication. If contraception is a high priority, check with your doctor to evaluate whether your medication interacts with your oral contraceptive, and if other forms of contraception need to be considered.
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