Filed under: Brain & Nervous System
Charcot (shahr-KOH)-Marie-Tooth disease, also known as hereditary motor and sensory neuropathy, is a group of hereditary disorders that affects the nerves in your arms and legs. The disease predominantly causes muscle weakness and decreased muscle bulk with typically limited decreased sensation. With Charcot-Marie-Tooth disease, symptoms may vary widely in severity, even among family members, but tend to slowly worsen over time.
Charcot-Marie-Tooth symptoms usually begin in your feet and legs, but may also eventually affect your hands and arms. Foot deformities such as hammertoes and high arches are common in Charcot-Marie-Tooth disease. Muscle weakness and loss of balance can make walking difficult. Symptoms of Charcot-Marie-Tooth disease typically appear in adolescence or early adulthood, but late onset also occurs.
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