ad info

CNNin
 MAIN PAGE
 WORLD
 ASIANOW
 U.S.
 LOCAL
 POLITICS
 WEATHER
 BUSINESS
 SPORTS
 TECHNOLOGY
 NATURE
 ENTERTAINMENT
 BOOKS
 TRAVEL
 FOOD
 HEALTH
 AIDS
 Alternative
 Cancer
 Diet & Fitness
 Heart
 Men
 Seniors
 Women
 STYLE
 IN-DEPTH

 Headline News brief
 daily almanac
 CNN networks
 CNN programs
 on-air transcripts
 news quiz

  CNN WEB SITES:
CNN Websites
 TIME INC. SITES:
 MORE SERVICES:
 video on demand
 video archive
 audio on demand
 news email services
 free email accounts
 desktop headlines
 pointcast
 pagenet

 DISCUSSION:
 message boards
 chat
 feedback

 SITE GUIDES:
 help
 contents
 search

 FASTER ACCESS:
 europe
 japan

 WEB SERVICES:
Health

Study: New 'super aspirin' cuts heart attack risk

Aspirin graphic June 22, 1998
Web posted at: 11:08 p.m. EDT (0308 GMT)

WASHINGTON (CNN) -- New "super aspirin" can effectively relieve angina and significantly reduce the risk of heart attacks, according to a study published Monday.

The study, in Circulation: Journal of the American Heart Association, looked at Lamifiban, a drug now in its last phase of testing before a final review by the U.S. Food and Drug Administration.

The first "super aspirin," Aggrastat, was approved by the FDA last month and is now in distribution.

The current treatment for angina -- chest pain caused by a poor blood supply to the heart muscle -- is conventional aspirin and a blood-thinning drug called heparin. The aspirin-heparin combination does not work in at least 10 percent of cases, and some patients go on to have a heart attack.

Unstable angina occurs when years of cholesterol buildup on artery walls suddenly causes a rupture and platelets clump around the wound. As the clot becomes larger, it blocks arterial blood flow to the heart and can lead to a heart attack.

Studies show that the new "super aspirin" drugs, especially when used in combination with aspirin and heparin, can significantly reduce the incidence of angina and heart attacks.

The latest study shows that Lamifiban has a greater long-term benefit rather than an immediate effect, meaning that it may not give a quick response when dealing with angina in an emergency situation. Angina is the leading reason for admitting people to coronary care units.

"Other things being equal, doctors will tend to use Aggrastat instead of Lamifiban because the immediate results with Aggrastat appear to be better than the results of Lamifiban," said Dr. Alan Geurci of St. Francis Hospital in Roslyn, New York. "Manufacturers of Lamifiban are going to have a hard sell."

Lamifiban is in Phase III clinical trials, which is usually the last step before seeking FDA approval. It will not be ready for distribution "at least until next year," according to its manufacturer, Hoffman-LaRouche Inc.

Aggrastat is manufactured by Merck & Co.

The Associated Press contributed to this report.
Related stories:
Latest Headlines

Today on CNN

Related sites:

Note: Pages will open in a new browser window

External sites are not
endorsed by CNN Interactive.

SEARCH CNN.com
Enter keyword(s)   go    help

  
 

Back to the top
© 2000 Cable News Network. All Rights Reserved.
Terms under which this service is provided to you.
Read our privacy guidelines.