Doctors use lasers to burst cancer cells
August 12, 1997
Web posted at: 10:48 p.m. EDT (0248 GMT)
From Correspondent Al Hinman
PITTSBURGH (CNN) -- A new cancer treatment combining laser
light with a light-sensitive chemical is providing a new ray
of hope to many cancer patients.
The treatment, called photodynamic therapy, combines the
intense, bright light produced by a laser with a
light-sensitive chemical called phototrin, which has a
special affinity for cancerous cells.
"The hemoglobin that's in our body has picked up that
chemical and when this specific laser light hits it, it
causes an explosion within the cancer cell," said Dr. Rodney
Landreneau of Allegheny General Hospital. "Since it's not
concentrated within normal cells, they are spared,
relatively."
Therapy could treat many tumors
The tumor-blasting procedure has won FDA approval to help
slow the progression of cancer of the esophagus, one of the
least curable and fastest-spreading cancers, which kills
11,000 Americans per year.
Doctors believe photodynamic therapy could also offer new
hope in treating many other tumors. For example, Allegheny
General doctors are trying it out in the treatment of lung
cancer, the biggest cancer killer in the United States.
"If it's an early cancer that involves the airway, this is a
potential option to surgery," Landreneau said.
Before this therapy became available, patients whose lung
cancer was diagnosed early enough to operate faced the loss
of part or all of a lung, as doctors cut out the cancer and
nearby tissue.
May improve quality of life
The effects of such surgery, combined with radiation and
chemotherapy, can be harrowing for those who survive.
Photodynamic therapy offers a chance for cancer patients to
improve their quality of life.
Dan Mariotti's lung cancer was at an advanced stage, and
doctors told him the new treatment might do little more than
ease his suffering. After a year and a half of treatments,
Mariotti died of complications caused by his advanced
illness.
But his doctor says the light therapy did improve his quality
of life, right up to the end. For others, doctors hope,
photodynamic therapy can offer much more, especially for
cancers caught and treated early.
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