He visited the Corpus Christi area, which was the point of initial landfall for Hurricane Harvey in the state.
Secretary of Labor Alexander Acosta, Secretary of Transportation Elaine Chao, Secretary of Energy Rick Perry, Secretary of Veterans Affairs David Shulkin and acting Secretary of Homeland Security Elaine Duke rode on Air Force Two with the vice president to Texas.
Under the blistering heat of open Texas skies, Pence made his first stop of the day in Rockport, where he was joined by Texas Gov. Greg Abbott. Pence stopped by a church that was badly damaged by the storm, First Baptist Church, where he was joined by evangelical pastor Franklin Graham.
The Cabinet secretaries and the vice president joined Graham in prayer, bowing their heads along with about 100 people from local congregations.
"There is no storm as tough as the people of Texas!" Abbott, who introduced Pence, told the crowd energetically. He declared this coming Sunday a day of prayer for the state.
Pence thanked the first responders and local officials, saying, "I also want to pay a debt of gratitude to all of those that have stepped forward and shown their work in this dark hour."
He added that he spoke to President Donald Trump on the plane en route to Texas, who told him that "We love Texas." Pence emphasized that Trump wanted Texans to know that the "full resources of the national government are being brought to bear in a consistent way."
As he shook hands after the short remarks, a few people broke down in tears as they hugged the vice president and shook hands. Many offerings of "God bless you" passed through the crowd. Pence looked flushed and emotional.
At another stop down the road in Rockport, Pence rolled up his sleeves as he met with victims of the storm whose homes were badly damaged. At one young couple's house, Pence pulled on blue work gloves and dragged tree branches out of a front lawn, sweat dripping down his nose.
At a news conference with Abbott, Pence told reporters that Trump will return to Texas on Saturday with first lady Melania Trump, and will travel to "Houston and other destinations" within the state.
On Tuesday, Trump visited Corpus Christi and Austin as he met with federal, state and local officials
about the ongoing rescue and recovery efforts after Hurricane Harvey made landfall over the weekend.
When aides advised Trump that visiting the hardest-hit areas would divert important resources from the recovery efforts, he settled on Corpus Christi, the coastal city which was spared the brunt of the damage.
It is not the first time Pence has visited natural-disaster ravaged regions. In August 2016, when he was governor of Indiana, he paused campaigning on the Trump ticket to visit regions of his state that were hit by tornadoes.
Harvey is projected to be one of the most expensive natural disasters
in US history. Two estimates on Wednesday put total losses -- including property damage, lost wages and disrupted business -- at as much as $75 billion.
Trump said earlier this week
that he believes Congress will act quickly to provide disaster relief funding to the areas affected by Harvey, predicting "very rapid action" on the matter.
While Pence served in Congress, he voted for the final package for Katrina relief in 2005, though he made comments on the House floor that expressed concern in raising taxes to fund it.
"We must ensure that a catastrophe of nature does not become a catastrophe of debt for our children and grandchildren, through introducing tough budget cuts like Operation Offset."
At the time, Pence was head of the House Republican Study Committee, a group of fiscal conservatives who were pressing for some spending cuts to pay for the relief package.
Pence would not say Thursday if Harvey aid should be offset by cuts from other places when asked if he still holds his 2005 belief.
"I was very pleased to support federal disaster funding in the wake of Hurricane Katrina, but in the months that followed that I was also a part of an effort in congress to find savings in the budget to pay for that," Pence told reporters.
"And I would leave those decisions to members of Congress and to the President of the United States as we move forward," Pence said.
The vice president repeatedly said the President's focus is currently on rescue and recovery efforts and would not say what the administration position on offsets is.
He was asked twice about whether the aide would need to be offset, and would not answer both times.