Republican voters expressed broad anger at the government, but Democratic voters said Wall Street was harming the economy, according to early exit poll results.
About four in 10 Democrats and Republicans each said the economy was their top issue. Government spending was a close second for Republicans -- about three in 10 said that was their top concern. The second-ranking issues for Democrats in Indiana were income inequality and health care, with about one quarter each saying that was most important to them.
About six in 10 Republicans said their primary has been more divisive, and three quarters of Democrats said their primary has been more energizing than divisive.
A majority of Republican voters said they feel "betrayed" by their party, but two-thirds said the nominating process has been fair.
Democrats in Indiana were about evenly split on whether international trade created jobs or cost jobs in the U.S.
There was a wide gender gap between Donald Trump and Ted Cruz, with women going for Trump 47%-41%, but men breaking for Trump 59%-33%.
Cruz's appearances in the state appeared to make little difference: voters who decided in the last week who they would vote for only broke for him 46%-42%
Cruz supporters (49%) also said their vote was against Trump, but 35% of Trump voters said their vote was against Cruz. College graduates narrowly supported Trump over Cruz, 46%-41%, but voters who did not graduate college supported Trump over Cruz 59%-34%.
Among Democrats, women split evenly between Hillary Clinton and Bernie Sanders, 50% each. But men broke for Sanders 57%-43%.
White voters went for Sanders 58%-42% over Clinton, and made up 73% of the electorate. But black voters, who made up 18% of the electorate, went for Clinton over Sanders 74%-26%.
Among Democrats, 86% said they were ready for a woman president, but among them Clinton only edged out Sanders 51%-49%.
And 31% of Democrats said they would be "excited" if Sanders were elected president, but only 16% said they would be "excited" if Clinton were elected president.