(CNN) -- Chelsea Handler, the foul-mouthed, alcohol-swilling, cutting, irreverent and occasionally naked host of E!'s hit talk show "Chelsea Lately," is taking her act and moving it to Netflix. Later this year and in 2015, she'll create some comedy and documentary specials and then in 2016 premiere another talk show.
The last episode of "Chelsea Lately" will air on Tuesday night.
In her seven-year run, Handler has made "Lately" the go-to place for fans wanting something a little tarter with their talk-show entertainment. Let Jimmy Fallon have the "nice" aura; Handler is just as soon exasperated with her show, her staff and even her guests as she is tickled.
At this point, who knows what she'll bring to her Netflix program, which -- given the on-demand nature of the service -- will almost certainly have a different format. Nevertheless, there's plenty about "Chelsea Lately" we hope carries over to Handler's next talk-show chapter.
Here are seven things we'll miss in the meantime:
1. She regularly bit the hand that presented her.
Handler laughed and made fun of the same things the rest of us joke about, even when those things -- the Kardashians, Ryan Seacrest -- happened to share a network with her. She didn't care, which was classic Chelsea. Of course, E! probably didn't mind either, because any publicity is good publicity -- even mockery of Seacrest's stature.
2. She was willing to make fun of herself, too.
3. Those strange shower sketches.
It's hard to imagine David Letterman -- or even Stephen Colbert -- being willing to engage in argumentative sketches with the likes of Sandra Bullock and Conan O'Brien while standing naked in a shower. (Judging from the fuzzed-out naughty bits, there's a minimum of special effects involved. Incidentally, nice abs, Conan.) Seems like Handler would be a natural to mount a revival of "Steambath."
4. Honestly, Jennifer Aniston.
On other talk shows, the former "Friends" star is like most other celebrities: sticking to the script (or the blue cards) and answering only what was discussed backstage with some assistant producer. But on "Chelsea Lately," she lets down her hair (so to speak), probably because Handler is a friend outside of the studio. She's even gotten choked up!
5. Well, hello there, guest.
One of Handler's long-running jokes is that she sleeps with almost all her guests, which in the case of 50 Cent probably actually happened. But she was happy to flirt with almost everybody, men and women alike.
6. International incidents!
It wasn't enough that Handler insulted Lupita N'yongo during the Oscars this year. That was on her Twitter account, which (presumably) won't be going anywhere. But how many other talk show hosts would offend a whole country? Chances are that Serbia isn't going to mind Handler's departure from E!.
7. What about Chuy?
Jesus Melgoza, aka Chuy Bravo, has been Handler's diminutive right hand for the run of the show. No word on whether he'll be joining her at Netflix -- TMZ says he isn't -- but in the meantime, fans will have to be satisfied with his recommendations on serving tacos, using Tinder and healthy living.
CNN's Breeanna Hare contributed to this story.