(CNN) -- A commercial tour bus crash Sunday afternoon left two people dead and at least eight injured in upstate New York, authorities tell CNN.
Two fatalities have been confirmed, according to New York State Police Troop E spokesman Mark O'Donnell, and many people have been taken to local hospitals with various injuries.
Video shot by CNN-affiliate WHAM showed a blocked highway packed with rescue teams, racing to get victims to ambulances and emergency vehicles. Meanwhile, the wreckage of the white tour bus could be seen through the trees on the road's shoulder. Crews were trying to pull the vehicle from the thick nest of vegetation where it had come to rest.
Initial reports indicated that a flat tire caused the driver to lose control, O'Donnell said, but added that an accident reconstruction team is on the scene to investigate the cause of the accident. It happened around 4:15 p.m. on the northbound side of Interstate 90, near the town of Cohocton in Steuben County,
Injured passengers were taken to several area hospitals, said Walter Feely with the volunteer fire department in Cohocton.
Noyes Memorial Hospital in Dansville, New York, had received at least eight patients from the crash by Sunday night, said Kelly Sylvester of the hospital's administration unit.
The tour bus was heading to Niagara Falls. It is owned by Bedore Tours of North Tonawanda, near Buffalo. The company's website says it has been providing tours to Niagara Falls since 1950.
CNN's Stephanie Gallman and Miguel Susana contributed to this report.