Los Angeles (CNN) -- The film "The Social Network" took home four awards Sunday night, including best motion picture - drama, at the Golden Globes.
The television series "Glee" also had a good night with three wins.
Aaron Sorkin accepted the award for best screenplay -motion picture for "The Social Network," which also won the best director award for David Fincher and best original score for a motion picture for Trent Reznor and Atticus Ross.
The hit Fox series "Glee" won best television series - comedy or musical while cast members Jane Lynch won for best actress in a supporting role and Chris Colfer accepted the award for best performance by an actor in a supporting role in a series, miniseries or motion picture made for television.
"I think I just dropped my heart somewhere between Natalie Portman and Julianne Moore," a stunned Colfer said in receiving the award for his performance as gay teen Kurt Hummel on "Glee."
A pregnant Natalie Portman won the best actress in a motion picture-drama award for "Black Swan." She joked about the bit part her fiance, Benjamin Millipied, had in the film in which he says he wouldn't sleep with her character.
"He's the best actor, it's not true, he totally wants to sleep with me," Portman laughed about Millipied, who is the father of her unborn child.
Favored actor Colin Firth received the best actor in a motion picture - drama award for "The King's Speech" while "The Kids Are All Right" won for best motion picture - comedy or musical. Paul Giamatti collected his second career Golden Globe winning best actor in a comedy or musical for "Barney's Version."
Welsh-born actor Christian Bale and actress Melissa Leo won best supporting actor and actress awards for their roles in the same film, boxing movie "The Fighter."
"Batman" and "Dark Knight" star Bale joked that he wasn't really sure who the Globes' organizers -- the Hollywood Foreign Press Association -- were, but now recognizes "how wise and perceptive those guys really are."
Steve Buscemi won for best performance by an actor in a television series - drama for his role on the freshman HBO show, "Boardwalk Empire" which also won for best television series - drama.
Robert De Niro was presented with the prestigious Cecil B. DeMille Award. The veteran actor received a standing ovation from the room full of stars. The actor went for the funny, thanking the Hollywood Foreign Press Association for offering him the award before reviewing his latest film, "Little Fockers."
"These movies are like my children," De Niro joked about his body of work. "Except you can't remake my children in 3-D to push up the grosses."
"The Big Bang Theory" actor Jim Parsons took home the award for best actor in a TV series - comedy or musical and an absent Laura Linney was awarded best actress in a TV series - comedy or musical for the Showtime original series "The Big C."
Actor Al Pacino won the Globe for best actor in a miniseries or motion picture made for television for his role as Jack Kevorkian in "You Don't Know Jack." Claire Danes was awarded best actress in a miniseries or motion picture made for television for her title role in "Temple Grandin."
Annette Bening received a big congratulatory kiss from husband Warren Beatty after winning the Golden Globe for best actress in a motion picture - comedy or musical for "The Kids Are All Right."
Bening thanked members of her cast and also sent love "to the 1962 Golden Globe winner for most promising actor, my husband Warren Beatty."
Katey Sagal was awarded the Golden Globe for best actress in a TV drama series for her role in "Sons of Anarchy." The award for best miniseries or TV movie went to Sundance's "Carlos," and "Toy Story 3" won for best motion picture - animated.
Comedian Ricky Gervais promised to push the envelope of acceptable TV humor in his second year as host of the glitzy dinner party at the Beverly Hilton Hotel. And push it he did, remarking that the evening would be "a night of partying and heavy drinking - or what Charlie Sheen calls 'breakfast.' "
Gervais also took shots at "The Tourist," "Sex and the City 2" and others in a opening monologue that elicited some moans and groans from the celebrity crowd.
The red carpet was awash with stars before the show, including an appearance by Michael Douglas who learned last week his treatments for throat cancer were successful.
"I'm feeling great," Douglas told CNN. "I just found out last week that the tumor's gone." The actor received a standing ovation when he handed out the final award of the evening.
The Golden Globes show kicked off the Hollywood awards season Sunday at the Beverly Hilton Hotel with 26 trophies handed out by an array of stars, including teenage pop sensation Justin Bieber.
CNN's Lisa Respers France contributed.