Gaza City, Gaza (CNN) -- Two Israelis were wounded Wednesday night in a shooting at Rimonim Junction, east of the West Bank city of Ramallah, the Israel Defense Forces said.
The suspected gunmen ambushed the Israeli car at around 11 p.m. (4 p.m. ET) causing it to swerve off the road.
The overturned vehicle was found riddled with bullets, Israeli National Police spokesman Micky Rosenfeld told CNN.
"Based on the crime scene evidence, the victims' wounds and the bullet holes in the vehicle we believe this is a terrorist attack," he added.
The military wing of Hamas claimed responsibility for the attack.
Israeli National Police and the IDF set up roadblocks and were searching for those responsible.
The victims, an Israeli man and woman in their 30s, were taken to a hospital where the man was listed in serious condition; the woman was lightly wounded.
The attack came a day after four Israelis -- including a pregnant woman -- were fatally shot on the West Bank. The Israeli military said Wednesday it is still looking for the shooters.
Wednesday's attack came on the eve of direct Israeli-Palestinian peace talks in Washington, where Israeli Prime Minister Benjamin Netanyahu and Palestinian Authority President Mahmoud Abbas both condemned the attacks.
"I will not let the terrorists block our path to peace, but as these events underscore once again, that peace must be anchored in security," Netanyahu told reporters in a joint news conference that included Abbas and U.S. President Barack Obama.
"What happened yesterday and what is happening today is also condemned," Abbas said. "We do not want any blood be shed."
CNN's Azadeh Ansari contributed to this story.