(CNN) -- Novak Djokovic breezed into the quarterfinals of the U.S. Open with a straight sets demolition of home hope Mardy Fish in their fourth round match at Flushing Meadows on Monday.
The Serbian third seed took just one hour and 50 minutes to complete a 6-3 6-4 6-1 win over Fish, who came into the final grand slam in the form of his life but was comprehensively outclassed on the Arthur Ashe Center Court.
"It was a great performance and my best so far in tournament," he told Sky Sports.
It earned Djokovic a quarterfinal clash with Gael Monfils, who beat Richard Gasquet 6-4 7-5 7-5 in an earlier all-French clash.
"I have a tough opponent, but the way I'm playing I have a good chance," added Djokovic, who has a career 4-0 advantage over Monfils and a fine record in New York.
Fish, who with Sam Querrey were the last American players in the men's singles draw, was always on the backfoot after giving up two early breaks to lose the first set.
A single break of service was enough to give Djokovic a two sets to love lead, and two more wrapped up the match in comprehensive style.
He was runner-up in 2007 and reached the semifinals for the past two years, each time losing to Roger Federer, who is a potential last four opponent again.
The world number two continued his perfect Flushing Meadows campaign with a 6-3 7-6 6-3 win over Austria's Jurgen Melzer.
The five-time champion is yet to drop a set in New York and he remains on course for a record-breaking sixth U.S. Open crown.
Monfils reached his third grand slam quarterfinal and became the first Frenchman into the last eight at this event since Arnaud Clement in 2000.
A single break of service was enough to give him a two-sets lead, but he was broken to trail 2-5 in the third until reeling off five winning games in a row.
Victory took just over two and a half hours and Monfils was pleased to stick with his game plan.
"My plan was to try to break him physically and break him in the head," Monfils told AFP. "I think I did pretty good."
Sweden's Robin Soderling fought back from losing the opening set to overcome Albert Montanes 4-6 6-3 6-2 6-3.
The fifth seed Soderling will meet Federer in the last eight, a repeat of their 2009 quarterfinal contest.