(CNN) -- A small plane crashed outside Muncie, Indiana, as military F-16s trailed it Wednesday after its pilot failed to respond to radio calls, the North American Aerospace Defense Command said.
The plane crashed into a farm field in Randolph County, Indiana, near the town of Winchester, about 12:40 p.m. ET, NORAD said in a statement. There were no reports that anyone on the ground was hurt.
There was one fatality, believed to be the pilot and sole occupant of the plane, the Indiana State Police said. The person's identity had not been confirmed as of Wednesday afternoon.
The incident was not believed to be terrorism-related and may be a medical situation, officials said. Watch CNN's Jeanne Meserve report on hypoxia, a deprivation of oxygen »
The F-16s, from the Indiana Air National Guard, intercepted the aircraft near Muncie about 11:30 a.m. ET, NORAD said in a statement.
The plane departed Grand Rapids, Michigan, and lost communication with ground air traffic controllers.
"Upon intercepting the aircraft, the F-16 pilots reported the pilot was unresponsive," the statement said.
Winchester is about 25 miles east of Muncie.
Footage taken by CNN affiliate WTHR over the crash site showed police and fire officials surrounding the charred wreckage, in what appeared to be tall rows of corn.
CNN's Barbara Starr, Mike Mount and Chad Myers contributed to this report.
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