(CNN) -- World number three Phil Mickelson upstaged Tiger Woods to take a two-stroke lead after the second round of the WGC-CA Championship at Doral's Blue Monster course in Florida on Friday.
Mickelson has led for two successive rounds as a six-under-par 66 kept him on top in Florida.
Mickelson, the joint overnight leader, carded a six-under-par 66 to lie on a 36-hole total of 131 (-13) -- with fellow-American Nick Watney (67) heading the chasing pack.
Kenny Perry carded a superb eight-under-par 64 to lie a stroke behind in third place, level with teenage Northern Irish sensation Rory McIlroy, who carded a 66.
Mickelson was one of four players who shared the lead after the opening round, but his three fellow-pacesetters endured rounds to forget.
Thailand's Prayad Marksaeng dropped four shots behind, Indian Jeev Milkha Singh fell five back after a double bogey at the final hole, while South African Retief Goosen matched the day's worst score to plunge 10 strokes off the pace.
Prayad actually led for the majority of his round, but a triple bogey at the par-four 18th ensured a dismal end to the day.
World number one Woods, in his first stroke play event since knee surgery last June, also had his problems, battling to a mediocre round of 70 to lie 10 shots off the pace.