(CNN) -- American John Rollins has opened up a three-stroke lead going into the final round of the Buick Invitational event at Torrey Pines.
Rollins remains on course to lift his first title since victory in the 2006 BC Open.
Rollins, bidding for his first title since the 2006 BC Open, birdied the second, fourth and sixth holes and traded two birdies and three bogeys on the back nine to move three shots ahead of second round leader Camilo Villegas with an overall score of 12-under-par 204.
Colombian Villegas had started with a one-stroke lead but bogeyed the seventh and double-bogeyed the ninth to go out at three-over 39.
Villegas, who won twice on tour last season, appeared to have trouble with the rainy and windy conditions early in the day and finished on two-over-par 74.
Nick Watney sits alone in third place after carding a one-under-par 71. Watney started the day in fourth and used a birdie on 17 to jump up a spot.
Briton Luke Donald (71) is tied for fourth with American Paul Goydos (72), six shots off the pace -- while Charles Warren was the big mover of the day, jumping from 32nd to a tie for sixth place with a four-under-par 68. Warren did much of his damage on the back nine, coming in at 33.
Lucas Glover carded a three-under-par 69 and Charley Hoffman, who began the day in third place, slumped to a two-over 74 to join Warren at seven shots back.
Phil Mickelson, who has won this event three times, bogeyed three of the first 11 holes and finished with a one-over-par 73 on the day to leave him at one- under overall.
British Open and PGA champion Padraig Harrington double-bogeyed the fourth and bogeyed the seventh and could not make up the deficit on the back nine, carding a second straight 74 to slip 15 shots off the pace. Harrington is playing in his first tournament of the season after having two non-malignant melanomas removed from near his right eye.