(CNN) -- Bayer Leverkusen went to the top of the German Bundesliga with a 4-0 thrashing of Nuremberg as defending champions Wolfsburg and Bayern Munich both drew on Saturday.
Bayer midfielder Simon Rolfes celebrates his penalty strike in the easy win.
Bayer never looked back after midfielder Toni Kroos scored from a free kick after just two minutes.
Fellow midfielder Simon Rolfes added a second from the penalty spot in the 23th minute and they were three up inside the first half when striker Eren Derdiyok netted on 34 minutes.
Steffan Kiessling headed home the fourth goal midway through the second half to boost the home side's goal difference.
SV Hamburg, who play bottom side Hertha Berlin on Sunday, will have to win by three of more goals to regain the leadership after Bayer's goal glut.
By contrast, Bavarian giants Bayern Munich have failed to score in three straight games for the first time in nine years after being held 0-0 at home by Cologne.
Bayern lost 1-0 at Hamburg last weekend and were held goalless by Juventus in the Champions League on Wednesday, but might have expected to beat Cologne, who are struggling near the bottom.
Bastian Schweinsteiger and Miroslav Klose both hit the woodwork in the first half at the Allianz Arena and further chances went begging after the break as Louis van Gaal's men trail the leaders by eight points.
Wolfsburg were held 1-1 at Bochum who took the lead early in the second half through Vahid Hashemian.
Edin Dzeko, who scored in Wolfsburg's 2-1 Champions League defeat to Manchester United, equalized to leave them sixth in the standings.
Elsewhere Hoffenheim's good recent run was ended with a 2-1 defeat to in-form Mainz while Hanover thrashed Freiburg 5-2.
Friday's action saw Schalke score a much-needed win after two defeats as they saw off Eintracht Frankfurt 2-0.
Goals from Gerald Asamoah and Jefferson Farfan lifted Schalke to third in the table.