(CNN) -- Wales scrum-half Dwayne Peel has been ruled out for the remainder of the Six Nations Championship with a torn hamstring.
Sale scrum half Peel will miss remainder of the Six Nations Championship.
Peel suffered the injury playing for his club side Sale Sharks against Newcastle on Sunday and will be replaced in the starting XV to face Italy in Rome on Saturday by Ospreys' Mike Phillips.
London Irish scrum-half Warren Fury has been called up to the squad as a replacement. Fury won two caps on Wales' tour of South Africa last summer.
Peel, who is set to be out for at least a month, will also miss the Six Nations finale against Ireland in Cardiff on Saturday week.
Reigning champions Wales were beaten by France in Paris in the latest round of matches, their first defeat in three games, but victories over Italy and unbeaten Ireland could yet see them retain the title .
England also received bad news when Wasps wing Paul Sackey was ruled out of their clash against France at Twickenham on Sunday.
Sackey is struggling with a lower calf muscle injury that forced him off during England's 14-13 defeat against Ireland at Croke Park 10 days ago.
He is likely to be replaced in the starting line-up by Harlequins' Ugo Monye or Sale Sharks back Mathew Tait.
Harlequins scrum-half Danny Care, meanwhile, will be involved against France despite receiving widespread criticism following the yellow card he collected for a reckless push on Ireland prop Marcus Horan in Dublin.
Center Shane Geraghty, meanwhile, will miss the rest of England's Six Nations campaign after breaking a bone in his hand playing for London Irish against Wasps at the weekend.
Meanwhile, Scotland have recalled Chris Paterson to their side for Saturday's clash with Ireland.
Paterson, Scotland's record points scorer and most capped player, did not find favor with coach Frank Hadden for the first three games of their Six Nations campaign.
He comes in for Edinburgh team-mate Hugo Southwell at full-back, one of two definite changes from the team which beat Italy just over a week ago as Hadden delays his final selection in the pack.
The other sees Alasdair Dickinson replace fellow prop Allan Jacobsen, who underwent shoulder surgery last week and will be out for up to four months.