(CNN) -- South Africa captain Graeme Smith is unlikely to take any further part in the third Test against Australia in Sydney after breaking a bone in his left hand during the second day's action.
Unlucky Smith will watch the rest of the final Test against Australia from the sidelines with a broken hand.
He retired hurt on 30 and was taken to hospital where x-rays confirmed the damage caused after a ball from Mitchell Johnson lifted and appeared to catch him on the knuckle.
Smith, who requires surgery on an elbow problem, returned with the hand in plaster to watch the closing overs as the Proteas ended on 125 for one in reply to Australia's first innings total of 445.
"When Graeme gets home next week he will be consulting our team and medical experts in Pretoria on the way forward for both the finger and his elbow," South Africa's media manager Michael Owen-Smith said.
"He's obviously disappointed to be injured but I think this is the kick he probably needed to take a bit of a rest," Harris added. "The big guy needs a rest. He's been playing for a long, long time and playing with a lot of pain (in his elbow)."
South Africa hope Smith will be available when Australia arrive for a re-match next month.
Michael Clarke earlier cracked a century as Australia battled to regain some pride after defeats in Perth and Melbourne saw them lose the three-Test series.
They are now looking to avoid their first home series whitewash loss in 122 years and Clarke's 142-run partnership with Johnson (64) gave them every chance of doing so.
Resuming on 77, Clarke showed his intent from the opening ball, cracking Makhaya Ntini through the covers for four.
Clarke, who was dropped on 12 and 69, brought up his 10th Test century with a quick single but at 138 the Australia vice captain gave a return catch to JP Duminy.
His purposeful knock -- a mix of exquisite drives, intelligent running and rigid defense -- lasted 373 minutes and included 17 fours.
Johnson, who was put down by Kallis on 18, hit 11 boundaries en route to his best score at Test level before being snapped up at first slip by Smith off Dale Steyn, who finished with figures of three for 95.
Peter Siddle (23) and Nathan Hauritz (41) kept the momentum going, the former cracking seven fours in a rousing knock before his appreciative home crowd.
Hauritz was last man out -- caught by Duminy off the bowling of Paul Harris (three for 94) -- just before tea.
South Africa will resume with Hashim Amla (30) and Jacques Kallis (36) batting on a pitch showing signs of wear and tear.
Neil McKenzie, who labored for nearly two hours over 23, was the only wicket to fall in the South African innings, trapped lbw by Siddle.