(CNN) -- Two men were in custody and a third was still on the run Friday after the shooting of two police officers in Indiana sparked a manhunt across the Ohio River into Kentucky, authorities said.
One of the injured officers is taken out of an ambulance and rushed into the University of Louisville Hospital.
Vincent Windell, 22, and another man whose name was not released were in custody in connection with Thursday's shooting, Jeffersonville, Indiana, Chief Detective Charlie Thompson told CNN.
A third suspect, Robert Dattilo, 37, fled into Kentucky, where Louisville police were pursuing him, according to Louisville Metro Police spokeswoman Alicia Smiley.
The incident began Thursday when Jeffersonville Police Cpl. Dan Lawhorn, 39, and Patrolman Keith Broady, 32, responded to a call from a Motel 6 employee about possible drug activity, Thompson said.
The two were apparently ambushed when they arrived, Indiana State Police told the Louisville Courier-Journal. Lawhorn, an 11-year veteran, was shot in the leg, and Broady, a 4-year veteran, was shot in the upper body, Thompson said.
The two officers returned fire, but it wasn't clear whether the suspects were hit. Lawhorn and Broady were able to reach their patrol cars and call for help after the shooting.
They were rushed to the University of Louisville Hospital for surgery and are both listed in serious but stable condition, hospital spokesman David McArthur told CNN.