The story

Sen. Joe Biden and Alaska Gov. Sarah Palin will face off for their first and only debate in the presidential race Thursday night, an event pitting a political veteran against a political newcomer.

Both candidates have recently tried to lower expectations leading into the debate, where topics will range from domestic to foreign policy.

The debate at Washington University in St. Louis, Missouri, will start at 9 p.m. ET and be moderated by PBS's Gwen Ifill. Read full article »

CNN's Sandra Endo, Peter Hamby, Ed Hornick and Alexander Mooney contributed to this report.

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