(CNN) -- Two children died as U.S.-led coalition forces stormed a compound in Afghanistan where a suspected Taliban militant had holed himself up with his young family, a military spokesman said Thursday.
Afghan forces, backed by coalition troops raided the compound in eastern Nangarhar province after receiving "credible intelligence" about militants in the area, said Maj. Chris Belcher, Combined Joint Task Forces-82 spokesman.
Belcher said troops were engaged in a firefight with the militant, after which the two children were found dead. Another child and a wounded adult female were also found, he said.
"While resisting multiple requests to surrender, the militant barricaded himself in a room. Unbeknownst to Afghan forces, his family was barricaded in the room with him," he said.
"It is regrettable when innocent lives are put at risk by militant forces. Our sincerest condolences go out to the families of the deceased and wounded."
Three people were detained in the incident.
Also Thursday, coalition troops and Afghan security forces "engaged and killed several Taliban fighters" after stumbling across militants preparing for attack in southern Afghanistan, Belcher said.
The fighting occurred near the Tarin Kowt district of the central province of Uruzgan, southwest of Kabul.
"Troops were conducting a reconnaissance patrol to protect the establishment of an Afghan security checkpoint when they surprised Taliban fighters setting up mortar positions,"he said.
Along with killing the insurgents, other "enemy fighters" fled.
"The increased number of attacks by the Taliban in recent days is a clear sign of their desperation," Belcher said.
NATO's International Security Assistance Force said on Thursday that "Afghan National Security Forces assisted by ISAF troops arrested more than a dozen of insurgents" on Wednesday in the western province of Badghis.
"Several people suspected of IED triggering and bomb making were among the arrested. In addition, the Afghan National Security Forces found illegal weapons such as rifles, mines and rocket-propelled grenades." E-mail to a friend