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(CNN) -- A bus hopped a highway median and crashed into a pickup truck before being broadsided by an 18-wheeler, Arkansas police said, killing the pickup driver and two bus riders.
Two passengers were found dead inside the bus, said Arkansas State Police.
Forty people were hurt in Sunday night's crash, which shut down a 13-mile stretch of Interstate-40 east of Forrest City, Arkansas, said state police spokesman Bill Sadler.
The bus was westbound en route from Chicago, Illinois, to Dallas, Texas.
The driver of the pickup truck -- identified as 30-year-old Danny Okurily of Hot Springs, Arkansas -- died at the scene of the accident, Sadler said. Bus driver Felix Tapia, 28, of Brownsville, Texas, and tractor-trailer driver David Rice, 45, of Mars Hill, North Carolina, suffered minor injuries, according to The Associated Press.
Two passengers were also found dead inside the bus, he said. Their names were not released because authorities have not yet notified relatives, Sadler said.
Several dozen injured passengers were taken to hospitals in Forrest City, Memphis and West Memphis, said police.
The bus, which listed 44 passengers on its manifest, was owned and operated by the Tornado Bus Line, which is based in Dallas, Texas, Sadler said.
The crash happened just after 10 p.m. CT about 10 miles east of Forrest City and about 40 miles west of Memphis, Tennessee, Sadler said. E-mail to a friend 
Copyright 2007 CNN. All rights reserved.This material may not be published, broadcast, rewritten, or redistributed. Associated Press contributed to this report.
All About Traffic Accidents • Arkansas
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