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LONDON, England (CNN) -- Long-haul flights have just got longer, with a non-stop flight from Singapore to New York now in operation.
But 18 hours in the air creates its own challenges.
A lot of preparation goes into the ultra long haul flight. The aircraft is specifically designed for the journey with more space and extensive entertainment services. The flight crew are also specially trained.
The seasoned traveler is also more aware of the health risks associated with a flight that covers as much as 16,600-kilometers (10,310-miles) in distance.
"Exposure to lower oxygen levels for up to 18, maybe 20, hours is abnormal for the human body," Farrol Kahn of the Aviation Health Institute told CNN.
"With deep vein thrombosis (DVT) the problem really starts occurring after 12 hours (in-flight). Now I would imagine that there is going to be an increase in heart attacks."
Kahn believes prevention is better than cure when it comes to in-flight health.
"The most obvious thing on the ultra long range flight is to provide passengers with flight socks and tablets for thinning the blood (if needed)," she explains.
It is not just the health and vitality of the passenger that is at stake on a flight of this length, but also that of the flight crew.
"They give us training on fatigue management and how to (adjust to) the local time in New York and to exercise, as well as take care our diet and eat lightly in-flight," says Linda Wee, a stewardess on Singapore Airlines.
However, passengers are trading in health concerns for convenience. An extra- long flight means passengers do not need to break up their journey and change planes.
"They like to board once, de-plane once. It is saving time," says James Boyd from Singapore Airlines.
"From Los Angeles to Singapore, passengers are saving two and a half hours. And to New York passengers are saving up to four hours in flying time."
Thai Airways is also launching a non-stop service to New York from Bangkok next June to compete with Singapore Airlines. It is planning a similar service to Chicago.
Cathay Pacific, Continental, Qantas and Emirates Airlines also offer flights that are more than 14 hours in duration. However, there is still a question of whether longer non-stop flights will become popular.
"They will certainly have a role in the future of aviation, there is no doubt about it. People will prefer to fly non-stop if it is available," says Chris Avery, an airline analyst at JP Morgan Chase bank.
"But we are reaching the limits. These markets are at the very margin of aviation. (Most) airlines still fly in the eight to 12-hour sector. This is still where the biggest volume (in traffic) is."
Avery believes that geography will determine the demand for the ultra long-haul flight and that worldwide appeal for this type of flight is unlikely.
"Asia is where the demand is for the ultra long-haul flight. (They are) connecting Asian cities to the U.S. East Coast, which is the big market," he explains.
"The routes that connect most places that European business travelers go do not need a capacity and endurance to fly 18-hours -- this is the same for U.S. carriers."
-- CNN's Richard Quest and Leone Lakhani contributed to this report