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Scientists find SARS virus, verify diagnostic test


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Mayo Clinic
SYMPTOMS
The World Health Organization alerts travelers to be aware of the symptoms, which include:
People after February 1 with a history of fever greater than 100.4 F (38 C) and one or more respiratory symptoms, including cough, shortness of breath, difficulty breathing and one or more of the following:
Close contact with a person who has been diagnosed with Severe Acute Respiratory Syndrome, or SARS. Close contact means having cared for, having lived with, or having had direct contact with respiratory secretions and body fluids of a person with SARS.
Recent history of travel to areas reporting cases of SARS.

LONDON, England (AP) -- Scientists are perfecting a test to diagnose a newly discovered virus believed to be responsible for the mystery illness that has sickened hundreds of people worldwide.

The World Health Organization said Saturday that advances by the University of Hong Kong and others are bringing scientists closer to determining how to treat severe acute respiratory syndrome, or SARS.

The progress comes less than a week after the WHO pulled together the talent from 11 laboratories around the world in an unprecedented collaboration to hunt down the disease.

"We can be relatively sure that we have now found the causative agent," said Dr. Klaus Stohr, a WHO virologist who is coordinating the global laboratory network.

"It is the SARS virus. But, to which virus family it belongs, we don't know yet," he added.

Some researchers believe it is a new type of paramyxovirus, but studies from other labs suggest it may belong to another virus family.

The virus, isolated from the lung tissue of a patient who died from SARS, is the basis for the diagnostic test, which Stohr said could be available to labs by the end of next week and in the hands of hospital doctors shortly afterward.

Diagnostic test

"This spectacular achievement is an example of what the world can do when the intellectual resources of nations around the world are focused on a single problem," Stohr said. "This rapid advance is fueling the hope that SARS can and will be contained."

The test would make it possible for doctors to quickly weed out and isolate patients with the new disease.

The development of the diagnostic test was announced Friday, but experts were cautious because the results had not been confirmed by further experiments. By Saturday its accuracy had been verified in eight more patients and more details were released.

"The consistency of these findings indicates that the test is reliably identifying cases of SARS infection," the WHO said.

SARS has made 386 people around the world ill and killed 11 people in the past three weeks, according to WHO figures. Experts suspect it is linked to an earlier outbreak of an unidentified disease in China, where officials say 305 people have fallen ill and five have died.

Two of the recent deaths occurred in Canada, where officials said Saturday they were investigating a third death from what they suspect is SARS.

Hong Kong remains the most seriously affected area, with more than half the total cases. Vietnam and Singapore have also been hit hard. The United States has reported 22 suspected cases, according to the latest WHO figures.

The State Department on Saturday warned Americans not to travel to Vietnam, one of the first countries affected.

In Hong Kong, health officials reported Sunday that three people had contracted SARS from a colleague in an office. Previously the disease had only spread between family members or hospital workers -- people in close contact with the sick.

Singapore said it would empty one of its main hospitals and dedicate it to coping with the disease.



Copyright 2003 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.

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